Results 261 to 270 of about 137,826 (378)

Homologous Recombination Deficiency in Ovarian and Breast Cancers: Biomarkers, Diagnosis, and Treatment. [PDF]

Curr Issues Mol Biol
Shah B, Hussain M, Seth A.
europepmc   +1 more source

Supplementary Table S3 from LP-184, a Novel Acylfulvene Molecule, Exhibits Anticancer Activity against Diverse Solid Tumors with Homologous Recombination Deficiency

Aditya Kulkarni, Jianli Zhou, Neha Biyani, Umesh Kathad, Partha P. Banerjee, Shiv Srivastava, Zsombor Prucsi, Kamil Solarczyk, Kishor Bhatia, Reginald B. Ewesuedo, Panna Sharma   +10 more
openalex   +1 more source

Telomerase Deficiency Affects the Formation of Chromosomal Translocations by Homologous Recombination in Saccharomyces cerevisiae

, 2008
Damon Meyer, Adam M. Bailis
openalex   +2 more sources

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Complex Relationships Between Homologous Recombination Deficiency (HRD) Score and Mutational Status of Homologous Recombination Repair (HRR) Genes in Prostate Carcinomas. [PDF]

Int J Mol Sci
Iyevleva AG, Aleksakhina SN, Sokolenko AP, Otradnova EA, Nikitina AS, Kashko KA, Syomina MV, Shestakova AD, Kuligina ES, Morozova NS, Popov SV, Vyazovcev PV, Luchkova TY, Peremyshlenko AS, Topuzov TM, Gudkova OM, Orlova RV, Levushkin AV, Moiseev DO, Shkodenko ON, Gubarev DV, Dzyuba AV, Povorina IY, Agaeva AV, Kutyan VF, Grigoryan MM, Orlov AN, Lefterov SI, Belousov AV, Nechaeva MN, Vorobyeva EN, Amirkhanova IK, Kryukova NV, Zatulivetrova LI, Gomboeva AB, Krivtsov VN, Shchiglik OI, Prokudina NV, Butunina NA, Belyaev AM, Imyanitov EN.   +40 more
europepmc   +1 more source

Organic neuromorphic electronics powering intelligent sensory and edge computing systems

InfoMat, EarlyView.
Organic electronic materials are promising candidates for neuromorphic sensing applications, including chemical, physical, visual, and multimodal sensing, owing to their mechanical softness, biocompatibility, and intrinsic ionic–electronic coupling.
Seungjun Woo, Minji Chung, Hyun Woo Song, Seoyoung Kim, Eun Kwang Lee, Joon Hak Oh   +5 more
wiley   +1 more source

Homologous recombination deficiency in breast cancer: genomic characteristics, clinical implications, and predictive value in neoadjuvant therapy. [PDF]

Front Oncol
Huang J, Luan F, Yan L, Liang X, Ma X, An Y, Hu S, Gao G, Wang Y, Yang J, Dong D.   +10 more
europepmc   +1 more source

Figure S7 from Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines [PDF]

Anne E. Dodson, Sol Shenker, Pamela Sullivan, Sumeet U. Nayak, Chris Middleton, Michael McGuire, Edmond Chipumuro, Yuji Mishina, Erica R. Tobin, Louise Cadzow, Andrew A. Wylie, Dipen Sangurdekar   +11 more
openalex   +1 more source

ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer.

Annals of Oncology, 2020
R. Miller, A. Leary, C. Scott, V. Serra, C. Lord, D. Bowtell, D. Chang, D. Garsed, J. Jonkers, J. Ledermann, S. Nik-Zainal, I. Ray-Coquard, S. Shah, X. Matías-Guiu, E. Swisher, L. Yates   +15 more
semanticscholar   +1 more source