Results 111 to 120 of about 709,830 (296)
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Isolation and characterization of cellulolytic bacteria from Lubimbi hot springs in Binga, Zimbabwe
Journal of BioScience and Biotechnology, 2023 Cellulolytic bacteria have gained worldwide interest due to their ability to secrete thermostable enzymes with multiple uses. In this study, cellulolytic bacteria were isolated from local hot springs on carboxymethyl cellulose (CMC ...
Reckson Kamusoko +3 more
doaj
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Commentary: MSH3 homology and potential recombination link to SARS-CoV-2 furin cleavage site
Frontiers in Virology, 2022 Yseulys Dubuy, Hugo Lachuer
doaj +1 more source
Homology and persistent homology
, 2020 Treballs Finals de Grau de Matemàtiques, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2020, Director: Francisco Belchí ...
openaire +1 more source
Discrete Mathematics, 1971 AbstractWith each bounded lattice L is associated a simplicial complex KL. If X is a cross-cut of L, then a simplicial complex KX is defined. It is shown that the geometric realizations of KX and KL are homotopy equivalent.
openaire +2 more sources
Let Σ0 and Σ1 be integral homology 3-spheres. They are said to be homology cobordant, or H-cobordant, if there exists a smooth compact oriented 4-manifold W with boundary ∂W= -Σ0 ∪ Σ1 such that the inclusions Σi → W induce isomorphisms H*(Σi, ℤ) → H*(W ...
Saveliev, Nikolai
core +1 more source
homology-semanticsimilarity: homology_analysis
, 2015 <p>Code, data, and results used for the homology manuscript.</p ...
Prashanti Manda
core +1 more source