Results 101 to 110 of about 660,490 (319)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Equidistribution of holonomy in homology classes for Anosov flows [PDF]
, 2017 We obtain equidistribution results for the holonomies of periodic orbits of Anosov flows lying in a prescribed homology class.
Sharp, Richard, Richard Sharp
core +1 more source
Pacific Journal of Mathematics, 1984 The author is concerned with the following question: Does every closed, orientable, irreducible 3-manifold M with \(\pi_ 1(M)\) infinite have a finite sheeted cover \(\tilde M\) with infinite \(H_ 1(\tilde M) ?\) Such an \(\tilde M\) would be a Haken manifold, so the positive answer to this question would imply existence of finite sheeted Haken covers ...
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Multiradial (multi)filtrations and persistent homology [PDF]
, 2016 Motivated by the problem of optimizing sensor network covers, we generalize the persistent homology of simplicial complexes over a single radial parameter to the context of multiple radial parameters.
Martin, Joshua M. +1 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Kunneth formuale in persistent homology [PDF]
, 2019 The classical Kunneth formula in homological algebra provides a link between the homology of a product space and that of its factors. We will show in this talk a collection of similar results for persistent homology.
Perea, José
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Invariants of 4-manifolds from Khovanov-Rozansky link homology [PDF]
, 2023 Ribbon categories are 3-dimensional algebraic structures that control quantum link polynomials and that give rise to 3-manifold invariants known as skein modules. I will describe how to use Khovanov-Rozansky link homology, a categorification of the gl(N)
Wedrich, Paul
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