Results 51 to 60 of about 1,026,270 (282)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells

open access: yesFrontiers in Pharmacology
Camellia oleifera is a medicine food homology plant widely cultivated in the Yangtze River Basin and southern China due to its camellia oil. Camellia oleifera bud and fruit exist simultaneously, and its bud is largely discarded as waste.
Jingming Niu   +10 more
doaj   +1 more source

Deteksi dan Evaluasi Keragaman Genetika Candidatus Liberibacter asiaticus sebagai Penyebab Penyakit Huanglongbing di Indonesia Berdasarkan Gen β-operon

open access: yesJurnal Fitopatologi Indonesia, 2017
Huanglongbing also known in Indonesia as citrus vein phloem degeneration (CVPD) is a devastating disease in citrus plantation worldwide, especially in Asia, Africa, and America.
Muhammad Rizal   +2 more
doaj   +1 more source

Tormentic acid, a triterpenoid isolated from the fruits of Chaenomeles speciose, protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway

open access: yesPharmaceutical Biology, 2023
Context Tormentic acid (TA), an effective triterpenoid isolated from Chaenomeles speciosa (Sweet) Nakai (Rosaceae) fruits, exerts an effective treatment for gastric damage.Objective To investigate the gastroprotective effect of TA on indomethacin (IND ...
Jun-Yu He   +13 more
doaj   +1 more source

Monopole Floer homology for rational homology 3-spheres

open access: yes, 2010
We give a new construction of monopole Floer homology for spin-c rational homology 3-spheres. As applications we define two invariants of certain smooth compact 4-manifolds with b_1=1 and b^+=0.Comment: 60 pages, to appear in Duke J. Math.
Froyshov, Kim A.
core   +1 more source

Homology stratifications and intersection homology [PDF]

open access: yesGeometry & Topology Monographs, 1999
A homology stratification is a filtered space with local homology groups constant on strata. Despite being used by Goresky and MacPherson [Intersection homology theory: II, Inventiones Mathematicae, 71 (1983) 77-129] in their proof of topological invariance of intersection homology, homology stratifications do not appear to have been studied in any ...
Rourke, Colin, Sanderson, Brian
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Reconsidering Cluster Bias in Multilevel Data: A Monte Carlo Comparison of Free and Constrained Baseline Approaches

open access: yesFrontiers in Psychology, 2018
The test for item level cluster bias examines the improvement in model fit that results from freeing an item's between level residual variance from a baseline model with equal within and between level factor loadings and between level residual variances ...
Nigel Guenole
doaj   +1 more source

Preparation and Quality Evaluation of Astaxanthin Gelatin-Gum Arabic Microspheres

open access: yesLiang you shipin ke-ji, 2022
This research aims to prepare Astaxanthin Gelatin-Gum Arabic microspheres and to explore its preparing technology and pharmaceutical properties. The Astaxanthin Gelatin-Gum Arabic microspheres were prepared by emulsion cross-linking method using gelatin ...
CHEN Yi-ying   +5 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Home - About - Disclaimer - Privacy