Results 71 to 80 of about 660,490 (319)

Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration

open access: yesFrontiers in Pharmacology
The herb pair Achyranthes bidentata Blume and Paeonia lactiflora Pall. (AB-PL) has demonstrated significant efficacy in the treatment of hypertensive cardiomyopathy; however, its underlying mechanisms remain unclear.
Yanyan Zhang   +14 more
doaj   +1 more source

Twisted homology [PDF]

open access: yesJournal of High Energy Physics, 2007
29 pages, 3 eps figures, added Report ...
Collinucci, Andrés, Evslin, JARAH J
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The 'Role' a Concept Plays in Science - The Case of Homology [PDF]

open access: yes, 2001
This article tries to clarify the idea that a concept plays a certain role for a scientific field or a research program. The discussion is based on a case study of the homology concept in biology.
Brigandt, Ingo
core  

Homology 3-Spheres [PDF]

open access: yes
Let R be a commutative ring with an identity element. By an R-homology 3-sphere we will mean a closed oriented 3-manifold M such that H* (M, R) = H*(S3, R).
Saveliev, Nikolai
core   +1 more source

Reliable and Cost-Effective QuEChERS–UHPLC–MS/MS Method for the Simultaneous Analysis of Ten Mycotoxins in Dendrobium Officinale: A Study on Food-Medicine Homology Quality Control

open access: yesJournal of Analytical Methods in Chemistry
This study developed a method for simultaneously detecting 10 mycotoxins in Dendrobium officinale using the QuEChERS technique combined with ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS). The method was optimized for
Zejun Wang   +6 more
doaj   +1 more source

Chinese bayberry (Morella rubra Lour.) seed improves DSS-induced inflammatory bowel disease by inhibiting inflammation and oxidative stress

open access: yesJournal of Functional Foods
This study investigated the phytochemical characteristics and first explored its anti-inflammatory action related to IBD of Chinese bayberry (Morella rubra Lour.) seed.
Dan Long   +8 more
doaj   +1 more source

Deteksi dan Evaluasi Keragaman Genetika Candidatus Liberibacter asiaticus sebagai Penyebab Penyakit Huanglongbing di Indonesia Berdasarkan Gen β-operon

open access: yesJurnal Fitopatologi Indonesia, 2017
Huanglongbing also known in Indonesia as citrus vein phloem degeneration (CVPD) is a devastating disease in citrus plantation worldwide, especially in Asia, Africa, and America.
Muhammad Rizal   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Reconsidering Cluster Bias in Multilevel Data: A Monte Carlo Comparison of Free and Constrained Baseline Approaches

open access: yesFrontiers in Psychology, 2018
The test for item level cluster bias examines the improvement in model fit that results from freeing an item's between level residual variance from a baseline model with equal within and between level factor loadings and between level residual variances ...
Nigel Guenole
doaj   +1 more source

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