Results 51 to 60 of about 1,015,655 (285)

Monopole Floer homology for rational homology 3-spheres

open access: yes, 2010
We give a new construction of monopole Floer homology for spin-c rational homology 3-spheres. As applications we define two invariants of certain smooth compact 4-manifolds with b_1=1 and b^+=0.Comment: 60 pages, to appear in Duke J. Math.
Froyshov, Kim A.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Eilenberg swindles and higher large scale homology of products of trees

open access: yes, 2016
We show that uniformly finite homology of products of $n$ trees vanishes in all degrees except degree $n$, where it is infinite dimensional. Our method is geometric and applies to several large scale homology theories, including almost equivariant ...
Diana, Francesca, Nowak, Piotr W.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells

open access: yesFrontiers in Pharmacology
Camellia oleifera is a medicine food homology plant widely cultivated in the Yangtze River Basin and southern China due to its camellia oil. Camellia oleifera bud and fruit exist simultaneously, and its bud is largely discarded as waste.
Jingming Niu   +10 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Structural characterization and hypolipidemic activity of polysaccharides from finger citron

open access: yesJournal of Functional Foods
In this study, the structural characterization and hypolipidemic activity in vivo of finger citron polysaccharide (FCP) were investigated. The FCP consisted of [→t)-Ara(f)-(1→], [→5)-Ara(f)-(1→], and [→4)-Gal(p)-UA-(1→] with the molecular weight of 46.35
Juan-Juan Ma   +5 more
doaj   +1 more source

COMPARATIVE ANALYSES OF MORPHOLOGICAL CHARACTERS IN SPHAERODORIDAE AND ALLIES (ANNELIDA) REVEALED BY AN INTEGRATIVE MICROSCOPICAL APPROACH

open access: yesFrontiers in Marine Science, 2015
Sphaerodoridae is a group of benthic marine worms (Annelida) characterized by the presence of spherical tubercles covering their whole surface. They are commonly considered as belonging to Phyllodocida although sistergroup relationships are still far ...
Conrad eHelm, Maria eCapa
doaj   +1 more source

Isolation of CYP72A154, a gene involved in glycyrrhizin biosynthesis pathway, in Glycyrrhiza glabra L. (Iranian licorice) [PDF]

open access: yesJournal of Medicinal Plants, 2022
Background: Cytochrome P450s have essential roles in oxidative reactions during the biosynthesis of secondary metabolites, such as terpenoids. Objective: This research was aimed to identify the gene CYP72A154 as a gene involved in the glycyrrhizin ...
Maryam Allahdou   +4 more
doaj  

Instanton Floer homology for two-component links

open access: yes, 2011
For any link of two components in an integral homology sphere, we define an instanton Floer homology whose Euler characteristic is the linking number between the components of the link.
Harper, Eric, Saveliev, Nikolai
core   +1 more source

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