Results 51 to 60 of about 709,830 (296)
Неофилология, 2023 The purpose of study is to identify the semantic and figurative parallels of the second part of Goethe’s “Faust” and B.L. Pasternak’s novel “Doctor Zhivago”.
S. A. Kornienko, O. V. Afanas’eva
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Homological properties of persistent homology
Journal of Algebra and Its ApplicationsIn this paper, we investigate to what extent persistent homology benefits from the properties of a homology theory. We show that persistent homology benefits from a Mayer–Vietoris sequence and a long exact sequence for a pair if one works with graded persistence modules.
Hani̇fe Varlı +2 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
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Stem Cell ResearchThe GPD1L gene is located on 3p22.3. It encodes the glycerol phosphate dehydrogenase 1-like protein with homology to glycerol phosphate dehydrogenase (GPD1L), but the function of this enzyme is unclear.
Tao Dong +6 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Cellular & Molecular Biology LettersBackground 20-Hydroxyecdysone (20E), a natural polyhydroxylated steroid found in various edible plants, exhibits diverse pharmacological effects. Pulmonary arterial hypertension (PAH) remains challenging to treat owing to its multifactorial pathogenesis.
Tong Lu +11 more
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Journal of Lipid Research, 2002 Development of the lipase gene family spans the change in science that witnessed the birth of contemporary techniques of molecular biology. Amino acid sequencing of enzymes gave way to cDNA cloning and gene organization, augmented by in vitro expression ...
Howard Wong, Michael C. Schotz
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Journal of High Energy Physics, 2007 29 pages, 3 eps figures, added Report ...
Collinucci, Andrés, Evslin, JARAH J
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The Role a Concept Plays in Science - The Case of Homology [PDF]
, 2003 The present paper gives a description and philosophical analysis of the conceptual variation in the homology concept. It is argued that different homology are concepts used in evolutionary and comparative biology, in developmental biology, and in ...
Brigandt, Ingo
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
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