Results 61 to 70 of about 709,830 (296)

Equivariant K-homology for some Coxeter groups

open access: yes, 2007
We obtain the equivariant K-homology of the classifying space \underline{E}W for W a right-angled or, more generally, an even Coxeter group. The key result is a formula for the relative Bredon homology of \underline{E}W in terms of Coxeter cells.
Sanchez-Garcia, Ruben
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Phytochemical analysis and anticancer effect of Camellia oleifera bud ethanol extract in non-small cell lung cancer A549 cells

open access: yesFrontiers in Pharmacology
Camellia oleifera is a medicine food homology plant widely cultivated in the Yangtze River Basin and southern China due to its camellia oil. Camellia oleifera bud and fruit exist simultaneously, and its bud is largely discarded as waste.
Jingming Niu   +10 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Persistent homology for 3D reconstruction evaluation [PDF]

open access: yes, 2012
Space or voxel carving is a non-invasive technique that is used to produce a 3D volume and can be used in particular for the reconstruction of a 3D human model from images captured from a set of cameras placed around the subject.
Monaghan, David S.   +10 more
core   +3 more sources

Structural characterization and hypolipidemic activity of polysaccharides from finger citron

open access: yesJournal of Functional Foods
In this study, the structural characterization and hypolipidemic activity in vivo of finger citron polysaccharide (FCP) were investigated. The FCP consisted of [→t)-Ara(f)-(1→], [→5)-Ara(f)-(1→], and [→4)-Gal(p)-UA-(1→] with the molecular weight of 46.35
Juan-Juan Ma   +5 more
doaj   +1 more source

COMPARATIVE ANALYSES OF MORPHOLOGICAL CHARACTERS IN SPHAERODORIDAE AND ALLIES (ANNELIDA) REVEALED BY AN INTEGRATIVE MICROSCOPICAL APPROACH

open access: yesFrontiers in Marine Science, 2015
Sphaerodoridae is a group of benthic marine worms (Annelida) characterized by the presence of spherical tubercles covering their whole surface. They are commonly considered as belonging to Phyllodocida although sistergroup relationships are still far ...
Conrad eHelm, Maria eCapa
doaj   +1 more source

Isolation of CYP72A154, a gene involved in glycyrrhizin biosynthesis pathway, in Glycyrrhiza glabra L. (Iranian licorice) [PDF]

open access: yesJournal of Medicinal Plants, 2022
Background: Cytochrome P450s have essential roles in oxidative reactions during the biosynthesis of secondary metabolites, such as terpenoids. Objective: This research was aimed to identify the gene CYP72A154 as a gene involved in the glycyrrhizin ...
Maryam Allahdou   +4 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration

open access: yesFrontiers in Pharmacology
The herb pair Achyranthes bidentata Blume and Paeonia lactiflora Pall. (AB-PL) has demonstrated significant efficacy in the treatment of hypertensive cardiomyopathy; however, its underlying mechanisms remain unclear.
Yanyan Zhang   +14 more
doaj   +1 more source

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