Results 121 to 130 of about 305,462 (309)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Augmentation powers and group homology

open access: yesJournal of Pure and Applied Algebra, 2004
It is well-known that low-dimensional group homology provides a useful tool for studying lower central series, dimension subgroups and augmentation powers of group rings. The aim of this paper is to extend these methods to the study of transfinite augmentation powers and, more generally, to the study of two-sided ideals in group rings and the normal ...
Mikhailov, Roman, Passi, Inder Bir S.
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Growth of torsion homology for arithmetic groups [PDF]

open access: yes, 2014
Non UBCUnreviewedAuthor affiliation: Institut de Mathematiques de ...
Bergeron, Nicolas
core  

On the regularity conjecture for the cohomology of finite groups [PDF]

open access: yes, 2008
Non peer ...
Benson, David J., David J. Benson
core   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

The cyclic homology of the group rings

open access: yesCommentarii Mathematici Helvetici, 1985
Let G be a discrete group. For \(x\in G\), denote by \(G_ x\) the centralizer of x and by \(N_ x\) the quotient of \(G_ x\) by the subgroup generated by x. Write \(=_ f\cup _{\infty}\) for the decomposition of the conjugacy classes of G into classes \(\bar x\) with the property that ord x\(
openaire   +2 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Homology groups of steiner systems

open access: yesJournal of Algebra, 1985
To each Steiner system (X,B) a finite simplicial complex K(X,B) is associated, whose homology groups afford a representation of the automorphism group of the system (in particular, projective and affine planes give the Steinberg representations of PSL(3,q) and of AFF(2,q)).
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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