Results 111 to 120 of about 305,462 (309)

The homotopy groups $\pi_k(\Omega_n(m))$, $k=1,...,n$

Researches in Mathematics
The paper continues the investigation of the spaces of complex-valued perfect splines $\Omega_n(m)$. These spaces were introduced as generalization of the spaces $\Omega_n$, the topology of which has been studied by V.I. Ruban, V.A. Koshcheev, A.M. Pasko.
A.M. Pasko
doaj   +1 more source

Algebraic Structures Based on a Classifying Space of a Compact Lie Group

Abstract and Applied Analysis, 2013
We analyze the algebraic structures based on a classifying space of a compact Lie group. We construct the connected graded free Lie algebra structure by considering the rationally nontrivial indecomposable and decomposable generators of homotopy groups ...
Dae-Woong Lee
doaj   +1 more source

Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes

BMC Biology, 2007
Background Upstream open reading frames (uORFs) can mediate translational control over the largest, or major ORF (mORF) in response to starvation, polyamine concentrations, and sucrose concentrations.
Jorgensen Richard A, Hayden Celine A
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

A Relation on Floer Homology Groups of Homology Handles

Tokyo Journal of Mathematics, 2006
The paper under review is to show a relationship on the rank of the Floer homology of integral homology handles. The Floer homology for homological \(S^2\times S^1\) is defined only for manifolds admitting a unique nontrivial \(SO(3)\), and its Floer relative index is no longer mod 8, but mod 4 period. The paper starts with observations from \textit{N.
openaire   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Trees and mapping class groups [PDF]

, 2009
There is a forgetful map from the mapping class group of a punctured surface to that of the surface with one fewer puncture. We prove that finitely generated purely pseudo-Anosov subgroups of the kernel of this map are convex cocompact in the sense of B.
Leininger, C., Leininger, Christopher J., Schleimer, Saul, Schleimer, S., Kent, R., Kent, Richard P.   +5 more
core   +1 more source

Using docking and alchemical free energy perturbation to determine the binding mechanism of eEF2K inhibitors and prioritizing the compound synthesis

Frontiers in Molecular Biosciences, 2015
A-484954 is a known eEF2K inhibitor with submicromolar IC50 potency. However, the binding mechanism and the crystal structure of the kinase remains unknown.
Qiantao eWang, Ramakrishna eEdupuganti, Clint D. J. Tavares, Kevin N. Dalby, Pengyu eRen   +4 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Molecular, proteomic and immunological parameters of allergens provide inclusion criteria for new candidates within established grass and tree homologous groups

World Allergy Organization Journal, 2015
Background Our knowledge of allergen structure and function continues to rise and new scientific data on the homology and cross-reactivity of allergen sources should be considered to extend the work of Lorenz et al., 2009 (Int Arch Allergy Immunol. 148(1)
Matthew D Heath, Joe Collis, Toby Batten, James W Hutchings, Nicola Swan, Murray A Skinner   +5 more
doaj   +1 more source