Results 31 to 40 of about 539,595 (279)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Trivial Homology Groups of Warped Product Semi-Slant Submanifolds in Kenmotsu Space Forms

open access: yesAxioms
This paper investigates the relationship between homology groups and warped product semi-slant submanifolds in Kenmotsu space forms. Some rigidity theorems for vanishing homology groups on warped product semi-slant submanifolds are obtained using the ...
Noura M. Alhouiti   +4 more
doaj   +1 more source

Categorification of the Kauffman bracket skein module of I-bundles over surfaces

open access: yes, 2004
Khovanov defined graded homology groups for links L in R^3 and showed that their polynomial Euler characteristic is the Jones polynomial of L. Khovanov's construction does not extend in a straightforward way to links in I-bundles M over surfaces F not D ...
Adam S Sikora   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The homology groups of the Cartesian product $\Omega_{n_1}(m_1)\times \Omega_{n_2}(m_2)$

open access: yesResearches in Mathematics
The paper continues the investigation of the spaces of complex-valued perfect splines $\Omega_n(m)$. These spaces were introduced as generalization of the spaces $\Omega_n$, the topology of which has been studied by V.I. Ruban, V.A. Koshcheev, A.M. Pasko.
A.M. Pasko
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling

open access: yesTumor Biology, 2017
Recent research indicates that the C-terminal Eps15 homology domain 1 is associated with epithelial growth factor receptor–mediated endocytosis recycling in non-small-cell lung cancer.
Dandan Tong   +7 more
doaj   +1 more source

Cloning and sequence analysis of E0 gene of virulent classical swine fever virus isolates in Shaanxi Province in 2006 — 2007

open access: yes浙江大学学报. 农业与生命科学版, 2010
According to the published genetic sequences of reference strain Shimen on GenBank, two pairs of primers were synthesized to amplify the E0 gene of nine prevalent virulent classical swine fever virus (CSFV) isolates from swine samples in Shaanxi Province
WU Xu-jin, ZHU Xiao-fu, CHEN De-kun
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On Homology Groups of a Subspace of Triangulations of the Two-Simplex with not More than 6 Subdivisional Boundary Vertices

open access: yesМоделирование и анализ информационных систем, 2013
We study homology groups of the space W˜₁(∇N ) of triangulations of the twodimensional simplex with vertices D₀D₁D₂ endowed with a boundary subdivision with not more than 6 vertices in case when this boundary subdivision is extended to the interior of ...
S. I. Yablokova
doaj   +1 more source

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