Results 31 to 40 of about 307,157 (265)
Tumor Biology, 2017 Recent research indicates that the C-terminal Eps15 homology domain 1 is associated with epithelial growth factor receptor–mediated endocytosis recycling in non-small-cell lung cancer.
Dandan Tong +7 more
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浙江大学学报. 农业与生命科学版, 2010 According to the published genetic sequences of reference strain Shimen on GenBank, two pairs of primers were synthesized to amplify the E0 gene of nine prevalent virulent classical swine fever virus (CSFV) isolates from swine samples in Shaanxi Province
WU Xu-jin, ZHU Xiao-fu, CHEN De-kun
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Моделирование и анализ информационных систем, 2013 We study homology groups of the space W˜₁(∇N ) of triangulations of the twodimensional simplex with vertices D₀D₁D₂ endowed with a boundary subdivision with not more than 6 vertices in case when this boundary subdivision is extended to the interior of ...
S. I. Yablokova
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Current Directions in Biomedical Engineering, 2021 Primary sclerosis cholangitis (PSC) predisposes individuals to liver failure, but it is challenging for radiologists examining radiologic images to predict which patients with PSC will ultimately develop liver failure.
Singh Yashbir +8 more
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A Spatiotemporal Brain Network Analysis of Alzheimer’s Disease Based on Persistent Homology
Frontiers in Aging Neuroscience, 2022 Current brain network studies based on persistent homology mainly focus on the spatial evolution over multiple spatial scales, and there is little research on the evolution of a spatiotemporal brain network of Alzheimer’s disease (AD).
Jiacheng Xing +4 more
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
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Sequence homology at the breakpoint and clinical phenotype of mitochondrial DNA deletion syndromes. [PDF]
PLoS ONE, 2010 Mitochondrial DNA (mtDNA) deletions are a common cause of mitochondrial disorders. Large mtDNA deletions can lead to a broad spectrum of clinical features with different age of onset, ranging from mild mitochondrial myopathies (MM), progressive external ...
Bekim Sadikovic +8 more
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
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Transfers for ramified covering maps in homology and cohomology
International Journal of Mathematics and Mathematical Sciences, 2006 Making use of a modified version, due to McCord, of the Dold-Thom construction of ordinary homology, we give a simple topological definition of a transfer for ramified covering maps in homology with arbitrary coefficients.
Marcelo A. Aguilar, Carlos Prieto
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