Results 41 to 50 of about 305,462 (309)

Trivial Homology Groups of Warped Product Semi-Slant Submanifolds in Kenmotsu Space Forms

open access: yesAxioms
This paper investigates the relationship between homology groups and warped product semi-slant submanifolds in Kenmotsu space forms. Some rigidity theorems for vanishing homology groups on warped product semi-slant submanifolds are obtained using the ...
Noura M. Alhouiti   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Simplicial methods and the homology of groups. [PDF]

open access: yes, 1997
PhDThis thesis generalizes the simplicial methods of defining derived functors and proves characterization theorems about them. In particular, we show that our methods also generalize an alternative way of defining derived functors, We use our ...
Modi, K
core  

K-theory for group C*-algebras [PDF]

open access: yes, 2011
These notes are based on a lecture course given by the first author in the Sedano Winter School on K-theory held in Sedano, Spain, on January 22-27th of 2007.
Baum, Paul, Sanchez-Garcia, Ruben
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling

open access: yesTumor Biology, 2017
Recent research indicates that the C-terminal Eps15 homology domain 1 is associated with epithelial growth factor receptor–mediated endocytosis recycling in non-small-cell lung cancer.
Dandan Tong   +7 more
doaj   +1 more source

Cloning and sequence analysis of E0 gene of virulent classical swine fever virus isolates in Shaanxi Province in 2006 — 2007

open access: yes浙江大学学报. 农业与生命科学版, 2010
According to the published genetic sequences of reference strain Shimen on GenBank, two pairs of primers were synthesized to amplify the E0 gene of nine prevalent virulent classical swine fever virus (CSFV) isolates from swine samples in Shaanxi Province
WU Xu-jin, ZHU Xiao-fu, CHEN De-kun
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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