Results 261 to 270 of about 46,167 (302)

Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases

Gene, 1990
The Saccharomyces cerevisiae gene (THR1) encoding homoserine kinase (HK; EC 2.7.1.39) was cloned by complementation in yeast. Disruption of the THR1 gene results in threonine auxotrophy in yeast. Comparison of the amino acid sequences of yeast and bacterial HKs reveals substantial similarity.
N P, Schultes, A D, Ellington, J M, Cherry, J W, Szostak   +3 more
openaire   +2 more sources

N-acyl homoserine lactone-mediated modulation of plant growth and defense against Pseudoperonospora cubensis in cucumber (Cucumis sativus L.).

Journal of Experimental Botany, 2020
N-acyl-homoserine lactones (AHLs), a well-described group of quorum sensing (QS) molecules, may modulate plant defense responses and plant growth.
S. Pazarlar, N. Cetinkaya, M. Bor, R. Kara   +3 more
semanticscholar   +1 more source

Balancing the AspC and AspA Pathways of Escherichia coli by Systematic Metabolic Engineering Strategy for High-Efficient l-Homoserine Production.

ACS Synthetic Biology
l-Homoserine is a promising C4 platform compound used in the agricultural, cosmetic, and pharmaceutical industries. Numerous works have been conducted to engineer Escherichia coli to be an excellent l-homoserine producer, but it is still unable to meet ...
Yuanyuan Chen, Liang-gang Huang, Tao Yu, Yuan Yao, Mingming Zhao, Aiping Pang, Junping Zhou, Bo Zhang, Zhiqiang Liu, Yuguo Zheng   +9 more
semanticscholar   +1 more source

L-Vinylglycine from L-Homoserine.

Synthetic Communications, 1988
Abstract A simple and practical synthesis of L-vinylglycine starting from L-homoserine is described.
PELLICCIARI, Roberto, NATALINI, Benedetto, MARINOZZI, Maura   +2 more
openaire   +1 more source

A Convenient Resolution of (±)-Homoserine to Afford Carbobenzoxy-D-Homoserine and D-Homoserine

Preparative Biochemistry and Biotechnology, 1981
Abstract D-Homoserine is an amino acid that has recently been found t o occur in the Nocardicin antibiotics. Herein we describe a simple resolution of the racemic material to afford carbobenzoxy-D-homo- serine via the L-tyrosinehydrazide salt and hence also D-homoserine itself.
openaire   +2 more sources

Bacillus megaterium CYP102A1 Oxidation of Acyl Homoserine Lactones and Acyl Homoserines

Biochemistry, 2007
Quorum sensing, the ability of bacteria to sense their own population density through the synthesis and detection of small molecule signals, has received a great deal of attention in recent years. Acyl homoserine lactones (AHLs) are a major class of quorum sensing signaling molecules. In nature, some bacteria that do not synthesize AHLs themselves have
Puneet K, Chowdhary, Neela, Keshavan, Hien Q, Nguyen, Julian A, Peterson, Juan E, González, Donovan C, Haines   +5 more
openaire   +2 more sources

Decreased homoserine levels in metabolic syndrome

Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2020
The pathogenesis Metabolic Syndrome (MetS), a common global problem, remains to be elucidated. As part of our exploratory metabolomics research we determined if homoserine levels are an early biomarker of nascent MetS.An exploratory study involving 28 patients with nascent MetS and 20 matched controls.
Ajay Patel, Lillian Abdelmalek, Austin Thompson, Ishwarlal Jialal   +3 more
openaire   +2 more sources

Biosynthesis of threonine from homoserine in pea seedlings: I. Homoserine kinase.

Plant Science Letters, 1978
Summary Homoserine kinase was partially purified from green shots of 2-week-old pea ( Pisum sativum L. cv. Pillert Fenomen) seedlings. The enzyme had an absolute requirement for both divalent (mg 2+ and Mn 2+ ) and monovalent (K + ) cations. The K m values of homoserine (6.7 mM) and ATp (2.7 mM) were much higher than for the enzyme from barley ...
A˚ge Thoen, Sven Erik Rognes, Aarnes Halvor   +2 more
openaire   +1 more source

Engineering of Phosphoserine Aminotransferase Increases the Conversion of l-Homoserine to 4-Hydroxy-2-ketobutyrate in a Glycerol-Independent Pathway of 1,3-Propanediol Production from Glucose.

Biotechnology Journal, 2019
Phosphoserine aminotransferase (SerC) from Escherichia coli (E. coli) MG1655 is engineered to catalyze the deamination of homoserine to 4-hydroxy-2-ketobutyrate, a key reaction in producing 1,3-propanediol (1,3-PDO) from glucose in a novel glycerol ...
Yujun Zhang, Chengwei Ma, W. Dischert, P. Soucaille, A. Zeng   +4 more
semanticscholar   +1 more source

Determination of homoserine as the lactone

Analytical Biochemistry, 1970
Abstract An accurate method for the analysis of homoserine has been developed which can be carried out in a reasonable time without requiring elaborate or expensive equipment. Homoserine is converted to the corresponding lactone by evaporation of the sample to dryness from a 3 N hydrochloric acid solution.
E, Voelkert, D R, Grant
openaire   +2 more sources