Results 1 to 10 of about 66,200 (304)
Genome‐Wide Homozygosity Predicts Inbreeding Depression in the Hihi/Stitchbird (Notiomystis cincta) Better Than Realised Load [PDF]
Evolutionary ApplicationsPopulation declines result in increasingly small populations, which often experience an increase in inbreeding. Inbreeding may be negatively associated with fitness traits like survival and reproduction, that is, inbreeding depression, and is therefore ...
Hui Zhen Tan +8 more
doaj +2 more sources
Runs of Homozygosity and Gene Identification in Pelibuey Sheep Using Genomic Data
Diversity, 2022 The runs of homozygosity (ROHs), the inbreeding coefficient, and the effective population size (Ne) in Pelibuey sheep were analyzed in 24 Pelibuey ewes from two lambs at parturition and 24 ewes that gave birth to a single lamb using the Ilumina ...
Wilber Hernández Montiel +2 more
exaly +3 more sources
Organ allocation and transplant equity in Brazil: the hidden burden of HLA homozygosity and hypersensitization [PDF]
Brazilian Journal of NephrologyIntroduction: Kidney transplantation remains the most cost-effective treatment for end-stage renal disease (ESRD); however, persistent organ scarcity and immunological barriers contribute to prolonged waiting times and inequitable access. Human leukocyte
Augusto Cesar Soares dos Santos Júnior +4 more
doaj +5 more sources
Frontiers in ImmunologyObjectiveIn a cooperative study of the University Hospital Leipzig, University of Leipzig, and the Charité Berlin on kidney transplant patients, we analysed the occurrence of HLA-specific antibodies with respect to the HLA setup of the patients. We aimed
Henry Loeffler-Wirth +2 more
exaly +3 more sources
Efficiency of Selection for Seed Cotton Yield under Newly Reclaimed Lands Conditions [PDF]
Journal of Plant Production, 2022 Selection for seed cotton yield plant-1 was applied in F2, F3 and F4-generations of a population of cross Giza 80 X Giza 90 cotton. The experiment was carried out during three successive summer seasons; 2019, 2020 and 2021 at farm west of Minia, El Minia
M. M. Abd El Majeed +3 more
doaj +1 more source
Identification of runs of homozygosity associated with male fertility in Italian Brown Swiss cattle
Frontiers in Genetics, 2023 Intensive selection for improved productivity has been accompanied by an increase in inbreeding rates and a reduction in genetic diversity. The increase in inbreeding tends to impact performance, especially fitness-related traits such as male fertility ...
Hendyel A. Pacheco +3 more
doaj +1 more source
Homozygosity and Linkage Disequilibrium [PDF]
Genetics, 2002 AbstractWe illustrate how homozygosity of haplotypes can be used to measure the level of disequilibrium between two or more markers. An excess of either homozygosity or heterozygosity signals a departure from the gametic phase equilibrium: We describe the specific form of dependence that is associated with high (low) homozygosity and derive various ...
Chiara, Sabatti, Neil, Risch
openaire +2 more sources
Animal, 2020 Hungarian Grey is an indigenous cattle breed that is one of the national symbols of Hungary. However, genetic description of the Hungarian Grey cattle has not yet been conducted based on whole-genome screening. Using the GeneSeek high-density Bovine SNP (
A. Zsolnai +5 more
doaj +1 more source
Pitfalls in Homozygosity Mapping [PDF]
The American Journal of Human Genetics, 2000 There is much interest in use of identity-by-descent (IBD) methods to map genes, both in Mendelian and in complex disorders. Homozygosity mapping provides a rapid means of mapping autosomal recessive genes in consanguineous families by identifying chromosomal regions that show homozygous IBD segments in pooled samples. In this report, we point out some
Miano MG +10 more
openaire +4 more sources
Association of IL-4 Polymorphisms with Allergic Rhinitis in Jordanian Population
Medicina, 2020 Background and objectives: Allergic rhinitis has complex patterns of inheritance, and single nucleotide polymorphisms, a common genetic variation in a population, exert a significant role in allergic rhinitis pathology.
Baeth Moh’d Al-Rawashdeh +3 more
doaj +1 more source