, 1977 Asymptomatic hyperlipemia occurs in a significant number of American children. It is important to recognize the condition during childhood because of its role as a risk factor in the early onset of coronary artery disease and because early dietary ...
Miller, William W.
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Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia
Vascular Health and Risk Management, 2012 Damon A Bell,1–3 Amanda J Hooper,1,2,4 Gerald F Watts,2,3 John R Burnett1–41Department of Core Clinical Pathology and Biochemistry, PathWest Laboratory Medicine, 2School of Medicine and Pharmacology, 3Lipid Disorders Clinic ...
Bell DA, Hooper AJ, Watts GF, Burnett JR
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Breaking barriers: Innovative therapies for managing homozygous familial hypercholesterolemia
Experimental and Molecular PathologyHomozygous familial hypercholesterolemia (HoFH) is a rare autosomal recessive disorder characterized by variants in genes involved in the regulation of low-density lipoprotein cholesterol (LDL-C) metabolism.
Shuai-Jie Huang +6 more
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Frontiers in PediatricsFamilial hypercholesterolemia (FH), particularly homozygous or compound heterozygous forms, predisposes individuals to premature cardiovascular disease due to severely elevated low-density lipoprotein cholesterol (LDL-C).
Ke Zhu +3 more
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Homozygous familial hypercholesterolemia (HoFH) in Germany: an epidemiological survey
ClinicoEconomics and Outcomes Research, 2013 S Walzer,1 K Travers,2 S Rieder,3 E Erazo-Fischer,3 D Matusiewicz41MArS Market Access and Pricing Strategy UG (hb), Weil am Rhein, Germany; 2United Biosource Corporation, Lexington, USA; 3Alcimed GmbH, Cologne, Germany; 4Institute for Health Care ...
Walzer S +4 more
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Porodična hiperkolesterolemija - mislimo li dovoljno o ovoj teškoj bolesti? [Familial hypercholesterolemia - do we think enough about this severe disease?] [PDF]
, 2013 Familial hypercholesterolemia is the most common genetic metabolic disorder and is associated with significant morbidity and mortality from cardiovascular disease, in particular coronary heart disease (CHD). Gene mutations for LDL receptor, APOB or PCSK9
Pećin, Ivan +2 more
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Liver transplantation for treatment of cardiovascular disease: Comparison with medication and plasma exchange in homozygous familial hypercholesterolemia [PDF]
, 1987 Brown +9 more
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The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research. [PDF]
, 2013 Elguindy, A, Yacoub, MH
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The genetics of familial hypercholesterolemia and emerging therapies
The Application of Clinical Genetics, 2015 Anja Vogt Medizinische Klinik und Poliklinik IV, Klinikum der Unversität München, Munich, Germany Abstract: Familial hypercholesterolemia (FH) results in very high levels of atherogenic low-density lipoprotein (LDL) cholesterol from the time ...
Vogt A
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Successful treatment of angina pectoris with liver transplantation and bilateral internal mammary bypass graft surgery in familial hypercholesterolemia [PDF]
, 1988 Brush, JE +4 more
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