Results 221 to 230 of about 30,354 (250)

Supravalvular Aortic Stenosis and the Risk of Premature Death among Patients with Homozygous Familial Hypercholesterolemia.

American Journal of Cardiology, 2021
Patients with homozygous familial hypercholesterolemia (HoFH) have a high risk for premature death. Supravalvular aortic stenosis (SVAS) is a common and the feature lesion of the aortic root in HoFH.
Ruiying Zhang, Jinjie Xie, Jie Zhou, Liyuan Xu, Yufan Pan, Yichen Qu, Rongjuan Li, Mei Chong, Li Song, W. Wen, Yue Wu, Jialu Li, Luya Wang, Ya Yang   +13 more
semanticscholar   +1 more source

Homozygous Familial Hypercholesterolemia

New England Journal of Medicine, 1975
Patients with homozygous familial hypercholesterolemia fall into two groups: one responds to diet and drug therapy; the other does not. Fibroblasts from patients in each group were compared for low-density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and low-density lipoprotein binding.
J L, Breslow, D R, Spaulding, S E, Lux, R I, Levy, R S, Lees   +4 more
openaire   +2 more sources

Homozygous familial hypercholesterolemia.

The Malaysian journal of pathology, 2014
We report a rare case of homozygous familial hypercholesterolemia (HoFH), a 22-year-old Malay woman who presented initially with minor soft tissue injury due to a cycling accident. She was then incidentally found to have severe xanthelasma and hypercholesterolemia (serum TC 15.3 mmol/L and LDL-C 13.9 mmol/L).
M K, Alicezah, R, Razali, T, Rahman, B P, Hoh, N H, Suhana, S, Muid, H M, Nawawi, M, Koshy   +7 more
openaire   +1 more source

Evinacumab for Homozygous Familial Hypercholesterolemia

New England Journal of Medicine, 2021
Frederick J, Raal, Daniel, Gaudet, Viktoria, Gusarova   +2 more
openaire   +5 more sources

Characteristics of homozygous familial hypercholesterolemia in Spain

Atherosclerosis, 2016
Genetic, Omics And In Silico Approaches.
Sánchez Hernández, Rosa M., Stef, M., Perez-Calahorra, S., Almagro, F., Saenz-Aranzubia, P., Plana Gil, Núria, Real Collado, Jose Tomas, Blanco-Vaca, Francisco, Ascaso Gimilio, Juan Francisco, Civeira Murillo, Fernando, Pocovi Mieras, Miguel   +10 more
openaire   +2 more sources

Plasma-Exchange Therapy of Homozygous Familial Hypercholesterolemia

New England Journal of Medicine, 1980
FAMILIAL hypercholesterolemia is a common, dominantly inherited disease characterized by increases in plasma cholesterol and low-density lipoproteins (LDL), xanthomas, and premature atherosclerosis...
M E, King, J L, Breslow, R S, Lees
openaire   +2 more sources

Homozygous Familial Hypercholesterolemia

Journal of Pediatric Endocrinology and Metabolism, 2009
Suhil A, Choh, Naseer A, Choh, Akhter, Rasool, Roomi, Yousuf, Umar, Qureshi   +4 more
openaire   +2 more sources

Management of Homozygous Familial Hypercholesterolemia

2020
Homozygous familial hypercholesterolemia (HoFH) is a devastating codominant autosomal disease mostly caused by loss off function variants affecting the LDL receptor gene (LDLR) and is characterized by extremely elevated plasma LDL-cholesterol (LDL-C), diffuse cutaneous and tendinous xanthomas, corneal arcus, and early diffuse atherosclerotic ...
openaire   +1 more source

Prevalence of Familial Hypercholesterolemia Among the General Population and Patients With Atherosclerotic Cardiovascular Disease

Circulation, 2020
Jacques Genest jr, Kausik K Ray, Antonio J Vallejo-Vaz   +2 more
exaly  

In Vivo AAV-CRISPR/Cas9–Mediated Gene Editing Ameliorates Atherosclerosis in Familial Hypercholesterolemia

Circulation, 2020
Huan Zhao, Lingjuan He, Wenjuan Pu
exaly