Utilidad de la ecografía de alta resolución en la valoración de la aterosclerosis preclínica, riesgo cardiovascular y diagnóstico de la hipercolesterolemia familiar [PDF]
, 2006 [spa] La presente tesis valora la utilidad de la ecografía carotídea de alta resolución, como técnica diagnóstica incruenta, útil, validada, reproducible y de bajo coste que nos permite:1.
Junyent Priu, Mireia
core +6 more sources
LDLR-Gene therapy for familial hypercholesterolaemia: Problems, progress, and perspectives [PDF]
, 2010 Coronary artery diseases (CAD) inflict a heavy economical and social burden on most populations and contribute significantly to their morbidity and mortality rates.
Charles Coutelle +11 more
core +1 more source
How do index patients participating in genetic screening programmes for familial hypercholesterolemia (FH) interpret their DNA results?:A UK-based qualitative interview study [PDF]
, 2011 OBJECTIVE: To explore patients' interpretations of their DNA results for familial hypercholesterolemia (FH). METHODS: In-depth interviews were conducted with patients from two lipid clinics in Scotland, who were offered genetic testing as part of a ...
Jenkins, Nick +6 more
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The panorama of familial hypercholesterolemia in Latin America: a systematic review[S]
Journal of Lipid Research, 2016 The burden caused by familial hypercholesterolemia (FH) varies among countries and ethnic groups. The prevalence and characteristics of FH in Latin American (LA) countries is largely unknown. We present a systematic review (following the PRISMA statement)
Roopa Mehta +6 more
doaj +1 more source
Patient with homozygous familial hypercholesterolemia: difficult to treat. Case report
, 2020 Homozygous familial hypercholesterolemia is a severe genetic disorder characterized by extremely high levels of total cholesterol and low-density lipoprotein cholesterol (LDL-C), as well as by rapid atherosclerosis progression in various vascular ...
Andrey V. Susekov +5 more
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Recent Advances on Familial Hypercholesterolemia in Children and Adolescents
Biomedicines, 2022 Familial hypercholesterolemia is a common autosomal hereditary disorder characterized by elevated concentrations of low-density lipoprotein cholesterol and the development of premature atherosclerosis and cardiovascular disease.
Francesca Mainieri +2 more
doaj +1 more source
Atherosclerosis Plus, 2021 Lomitapide, a drug for the treatment of homozygous familial hypercholesterolemia patients, reduced total and LDL cholesterol but no significant changes were observed on PCSK9 and Lp(a) plasma levels.
Maria Giovanna Lupo +11 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Information on the real‐world use of proprotein convertase subtilisin kexin 9 inhibitors (PCKS9is) in familial hypercholesterolemia are limited.
Marcello Arca +9 more
doaj +1 more source
Evinacumab for Pediatric Patients With Homozygous Familial Hypercholesterolemia [PDF]
CirculationAlbert Wiegman +2 more
exaly +2 more sources
Familial hypercholesterolemia: A review
Annals of Pediatric Cardiology, 2014 Familial hypercholesterolemia (FH) is a genetic disorder of lipoprotein metabolism resulting in elevated serum low-density lipoprotein (LDL) cholesterol levels leading to increased risk for premature cardiovascular diseases (CVDs).
Mithun J Varghese
doaj +1 more source