Results 1 to 10 of about 59 (55)

The Roles of GABA in Ischemia-Reperfusion Injury in the Central Nervous System and Peripheral Organs. [PDF]

open access: yesOxid Med Cell Longev, 2019
Ischemia‐reperfusion (I/R) injury is a common pathological process, which may lead to dysfunctions and failures of multiple organs. A flawless medical way of endogenous therapeutic target can illuminate accurate clinical applications. γ‐Aminobutyric acid (GABA) has been known as a marker in I/R injury of the central nervous system (mainly in the brain)
Chen C   +5 more
europepmc   +2 more sources

Pantothenic Acid Derivatives Modulate Oxidative Stress and Hepatic Fibrosis in Bile Duct Ligation-Induced Cholestatic Liver Injury [PDF]

open access: yesPathophysiology
Background/Objectives: Inflammation and oxidative stress are key factors contributing to the initiation and progression of liver fibrosis in chronic obstructive cholestasis.
Dmitry S. Semenovich   +11 more
doaj   +2 more sources

Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. [PDF]

open access: yesJ Biomed Biotechnol, 2005
With about 200 000 phytochemicals in existence, identifying those of biomedical significance is a mammoth task. In the postgenomic era, relating metabolite fingerprints, abundances, and profiles to genotype is also a large task. Ion analysis using Fourier transformed ion cyclotron resonance mass spectrometry (FT‐ICR‐MS) may provide a high‐throughput ...
Mungur R   +3 more
europepmc   +2 more sources

Muscle activity and emotional behavior changes in rats with chronic brain ischemia via comprehensive pathogenetic correction

open access: yesJournal of Education, Health and Sport, 2023
Cerebrovascular pathology has evolved from a medical concern to a social issue, with the efficacy of secondary neuroprotection remaining a pertinent question.
V. Kirchev
doaj   +1 more source

Cognitive function restoration in rats with chronic brain ischemia using Semax and hopantenic acid comprehensive administration

open access: yesJournal of Education, Health and Sport, 2023
The relevance and importance of treating patients with ischemic brain lesions are indisputable. Chronic ischemic processes in the brain occur much more frequently than acute cerebral circulation disorders, leading to prolonged disability and being the ...
V. Kirchev
doaj   +1 more source

PATHOPHYSIOLOGICAL ASPECTS OF HABILITATION AND REHABILITATION OF CHILDREN FROM CHILDREN’S HOMES WITH NEURODEVELOPMENTAL DELAY OF PSYCHOSOCIAL GENESIS

open access: yesБайкальский медицинский журнал, 2023
Background. Psycho-emotional stress in institutionalized children leads to significant tension in regulatory systems. Justification for using a complex of habilitation and rehabilitation measures aimed at reducing the stress factor and cre-ating ...
Anna V. Dubovaya, Sergey Ya. Iaroshenko
doaj   +1 more source

Management of Children with Speech Disorders via Transcranial Magnetic Stimulation: Non-Randomized Controlled Study

open access: yesПедиатрическая фармакология, 2023
Background. Speech development impairment is urgent and common problem in pediatric neurology. Transcranial magnetic stimulation (TMS) is one of the promising treatment variants for children with speech disorders. Objective.
Julia V. Nesterova   +21 more
doaj   +1 more source

CLINICAL AND NEUROLOGICAL MANIFESTATIONS OF DRUG-RESISTANT EPILEPSY AND OPTIMIZATION OF PATIENT TREATMENT

open access: yesЭпилепсия и пароксизмальные состояния, 2019
Aim – to study the clinical and neurological manifestations in patients with drug-resistant epilepsy and optimize the therapy. Materials and methods. Fifty patients with drug-resistant epilepsy were examined.
Yo. N. Madjidova   +2 more
doaj   +1 more source

Efficacy of hopantenic acid in the combined treatment of patients with neurogenic bladder dysfunction

open access: yesМедицинский совет, 2014
Neurogenic bladder dysfunction (NBD) has long remained one of the most topical problems in pediatric urology. This is explained by the steady growth in the number of patients.
I. V. Aleshin, Y. E. Zaytsev
doaj   +1 more source

ATTENTION DEFICIT HYPERACTIVITY DISORDER: MODERN PRINCIPLES OF DIAGNOSTICS AND TREATMENT

open access: yesВопросы современной педиатрии, 2014
One of 20 modern children and teenagers has attention deficit hyperactivity disorder (ADHD). New diagnostic criteria of ADHD according to DSM-V classification which contain the following main changes are considered in the article: age of onset — to 12 ...
N. N. Zavadenko
doaj   +1 more source

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