Results 41 to 50 of about 96 (69)

[23] Measurement of pantothenic acid and hopantenic acid by gas chromatography-mass spectroscopy

Methods in Enzymology, 1997
K Banno
exaly   +2 more sources

Simultaneous determination of pantothenic acid and hopantenic acid in biological samples and natural products by gas chromatography-mass fragmentography

Biomedical Applications, 1990
A method for the simultaneous determination of pantothenic acid and hopantenic acid in plasma samples was developed using gas chromatography-mass spectrometry with multiple ion detection. Plasma samples were directly purified without deproteinization on an ion-exchange resin, and the eluate was extracted with ethyl acetate under acidic conditions.
K Banno
exaly   +3 more sources

Hopantenic acid: perspectives for its use in psychiatry

Consilium Medicum, 2018
Yu.V. Bykov, R.A. Bekker
exaly   +2 more sources

The Neurotropic, Anti-Inflammatory, and Antitumor Properties of the Hopantenic Acid Molecule Based on Chemoinformatic Analysis

Neuroscience and Behavioral Physiology, 2016
Hopantenic acid is a known nootropic agent with a chemical structure close to that of pantothenic acid (vitamin B5). The neurotropic effect of hopantenic acid may occur as a result of binding with δ and κ opioid receptors, modulating acetylcholine secretion, and interacting with dopamine receptors.
O A Gromova, I Yu Torshin, A N Gromov
exaly   +2 more sources

Aduvant therapy of depression with hopantenic acid

Medical alphabet, 2022
Adequate SSRI monotherapy does not produce a sufficient clinical effect in some patients, and about 30% of patients do not respond to therapy at all. Favorable experience of combined prescription of SSRIs with various nootropic (neuroprotective) agents has been described in the literature.The aim of the study was to investigate the efficacy and ...
openaire   +1 more source

Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova, 2015
To evaluate the efficacy and safety of D-, L-hopantenic acid (pantogam active) on cognitive and anxiety disorders in patients with arterial hypertension.Autors selected 80 inpatients of a cardiology department with the verified diagnosis of hypertension and comorbid cognitive and anxiety disorders (50 patients in the main group, 30 patients in the ...
A B Smulevich, B A Volel
exaly   +4 more sources

Method development and validation of an HPLC assay for the detection of hopantenic acid in human plasma and its application to a pharmacokinetic study on volunteers

Acta Chromatographica, 2011
Summary A reliable and sensitive reversed-phase high performance liquid chromatography (RP-HPLC) with ultraviolet (UV) detection method was developed and validated for the quantification of hopantenic acid in human plasma. Hopantenic acid, with protocatechuic acid as the internal standard (IS), was extracted from plasma samples using a liquid-liquid ...
Olga N Pozharitskaya, Vera M Kosman, Alexander N Shikov   +2 more
exaly   +2 more sources

Attention deficit hyperactivity disorder in children: effectiveness of hopantenic acid pharmacotherapy

Voprosy Prakticheskoi Pediatrii, 2018
N N Zavadenko
exaly   +2 more sources

Application of Photogenerated Titrants for Determining Hopantenic Acid in a Solid Dosage Form

Pharmaceutical Chemistry Journal
E V Turusova, Turusova E V
exaly   +2 more sources

Pharmacotherapy of Attention Deficit Hyperactivity Disorder in Children: Results of a Multicenter, Double-Blind, Placebo-Controlled Trial of Hopantenic Acid

Neuroscience and Behavioral Physiology, 2018
Objectives. To assess the efficacy and safety of hopantenic acid (Pantogam) compared with placebo in the treatment of ADHD for four months in children aged 6–12 years during a prospective, multicenter, comparative, double-blind, placebo-controlled, parallel-group trial. Materials and methods.
N N Zavadenko, N Yu Suvorinova, E V Malinina   +2 more
exaly   +2 more sources