Results 61 to 69 of about 96 (69)

Analytical studies on the chiral separation and simultaneous determination of pantothenic acid and hopantenic acid enantiomers in rat plasma by gas chromatography—mass fragmentography: a reply

Biomedical Applications, 1992
E, Küsters, C, Spöndlin, C, Eder
exaly   +3 more sources

[Pharmacokinetics of hopantenic acid upon peroral administration].

Eksperimental'naia i klinicheskaia farmakologiia, 2010
A simple, specific and sensitive RP-HPLC method with UV detection for the determination of hopantenic acid in human blood plasma has been developed. The pharmacokinetics of drug pantocalcin upon single peroral administration was investigated on 18 healthy volunteers. The peak of hopantenic acid in blood plasma was achieved at 1.56 h and the elimination
M V, Karlina, O N, Pozharitskaia, V M, Kosman, A N, Shikov, M A, Lazukina, G I, D'iachuk   +5 more
openaire   +1 more source

Mass spectrometric identification of 2-hydroxydodecanedioic acid and its homologues in urine from patients with hopantenate therapy during clinical episode

Biological Mass Spectrometry, 1990
Urine from patients with calcium-4-(2,4-dihydroxy-3,3-dimethylbutyramido) butyrate hemihydrate (hopantenate) therapy during episodes of Reye's-like syndrome was found to contain a number of unusual dicarboxylic acids in high concentrations; odd- and even-numbered medium-chain dicarboxylic acids, alpha-hydroxydicarboxylic acids and beta ...
M, Matsumoto, T, Kuhara, Y, Inoue, T, Shinka, I, Matsumoto, M, Kajita   +5 more
openaire   +2 more sources

Possible applications of rac-hopantenic acid in the treatment of cognitive, anxiety and depressive disorders in patients with essential arterial hypertension

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018
Essential arterial hypertension (AH) is one of the main risk factors for the development of cognitive impairment and dementia. Cognitive decline is an early sign of brain damage as a target organ of hypertension, it occurs even in patients with uncomplicated hypertension with minimal duration of disease.
openaire   +2 more sources

Tardive dyskinesia and neurotransmitters: effects of sodium valproate, cyproheptadine, oxypertine, hydroxyzine pamoate and Ca-hopantenate on monoamine metabolites, cyclic nucleotides and gamma-aminobutyric acid in human cerebrospinal fluid.

Clinical therapeutics, 1985
Lumbar cerebrospinal fluid (CSF) homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA), cyclic AMP (cAMP) and cyclic GMP (cGMP) were measured in chronic schizophrenics with tardive dyskinesia before and three weeks after the initial treatment with sodium valproate (VPA), cyproheptadine, oxypertine or ...
T, Ogawa, T, Nagao, K, Kashiwabara, Y, Fujiwara, T, Harada, S, Otsuki   +5 more
openaire   +1 more source

The use of a hopantenic acid preparation for correction of cognitive disorders in the postoperative period in children

Voprosy praktičeskoj pediatrii, 2017
M.V. Panteleeva, A.М. Ovezov, A.S. Kotov, M.N. Borisova, A.V. Lugovoy   +4 more
openaire   +1 more source

Study of the effectiveness of using hopantenic acid in treatment of functional asthenia in children primary school age

Voprosy praktičeskoj pediatrii, 2018
L.S. Chutko, S.Yu. Surushkina, E.A. Yakovenko, T.I. Anisimova, M.B. Volov   +4 more
openaire   +1 more source

Urinary organic acids in elderly Japanese patients with ketosis and encephalopathy who have taken panto-yl-gamma-aminobutyrate, calcium salt (calcium hopantenate, HOPA)

Clinica Chimica Acta, 1990
T, Nakanishi, S, Funahashi, A, Shimizu, A, Hayashi   +3 more
openaire   +2 more sources

Measurement of pantothenic acid and hopantenic acid by gas chromatography-mass spectroscopy.

Methods in enzymology, 1997
openaire   +1 more source