Results 91 to 100 of about 384,646 (364)
Global extent of horizontal gene transfer [PDF]
Proceedings of the National Academy of Sciences, 2007 Horizontal gene transfer (HGT) is thought to play an important role in the evolution of species and innovation of genomes. There have been many convincing evidences for HGT for specific genes or gene families, but there has been no estimate of the global extent of HGT.
In Geol Choi, Sung-Hou Kim
openaire +2 more sources
Infection and Drug Resistance, 2014 Jennifer R HuddlestonBiology Department, Abilene Christian University, Abilene, TX, USAAbstract: Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic resistance among pathogens.
Huddleston JR
doaj
Gene cluster analysis method reliably identifies horizontally transferred genes and reveals their involvement in operon formation [PDF]
arXiv, 2006 The formation mechanism of operons remains controversial despite the proposal of many models. Although acquisition of genes from other species, horizontal gene transfer, is considered to occur, definitive concrete cases have been unavailable. It is desirable to select horizontally transferred genes reliably and examine their relationship to operons. We
arxiv
Genomic islands: tools of bacterial horizontal gene transfer and evolution [PDF]
, 2017 Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer. Besides the core genes encoding essential metabolic functions, bacterial genomes also harbour a number of accessory genes acquired by horizontal gene transfer that ...
Crook, Derrick W. +5 more
core
Arthritis Care &Research, EarlyView.Objective Despite knowledge that health outcomes vary according to patient characteristics, identity, and geography, including underrepresented populations in arthritis research remains a challenge. We conducted interviews to explore how researchers in arthritis have used equity, diversity, and inclusion (EDI) principles to inform their research ...
Megan M. Thomas +8 more
wiley +1 more source
The infinitely many genes model with horizontal gene transfer [PDF]
arXiv, 2013 The genome of bacterial species is much more flexible than that of eukaryotes. Moreover, the distributed genome hypothesis for bacteria states that the total number of genes present in a bacterial population is greater than the genome of every single individual. The pangenome, i.e.
arxiv
Interference plasmids and their use in combating bacterial resistance [PDF]
, 2019 Fighting against pathogenic bacteria that are resistant to antibiotics has become critical for health care worldwide. More than half a million people die every year from infections caused by drug resistant bacteria.
A. Zhivich, A. Zhivich
core +3 more sources
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
Chromosome architecture constrains horizontal gene transfer in bacteria.
PLoS Genetics, 2018 Despite significant frequencies of lateral gene transfer between species, higher taxonomic groups of bacteria show ecological and phenotypic cohesion. This suggests that barriers prevent panmictic dissemination of genes via lateral gene transfer. We have
Heather L Hendrickson +3 more
doaj +1 more source