Results 91 to 100 of about 5,536,538 (293)

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li   +17 more
wiley   +1 more source

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham   +7 more
wiley   +1 more source

Horizontal Gene Transfer and the History of Life [PDF]

open access: yes, 2016
Microbes acquire DNA from a variety of sources. The last decades, which have seen the development of genome sequencing, have revealed that horizontal gene transfer has been a major evolutionary force that has constantly reshaped genomes throughout ...
Daubin, Vincent, Szöllősi, Gergely J.
core   +2 more sources

Synthetic Fatty Acids Prevent Plasmid-Mediated Horizontal Gene Transfer

open access: yesmBio, 2015
Bacterial conjugation constitutes a major horizontal gene transfer mechanism for the dissemination of antibiotic resistance genes among human pathogens.
María Getino   +7 more
doaj   +1 more source

Vertical and horizontal gene transfer in lichens [PDF]

open access: yes, 2013
Lichens are symbiotic organisms, which consist of a mycobiont (fungus) and a photobiont (green alga or cyanobacteria). They inhabit a wide range of ecological niches.
KORAČ, PETRA, TUNJIĆ, MONIKA
core  

Horizontal Gene Transfer Phylogenetics: A Random Walk Approach

open access: yes, 2020
Sevillya G, Dörr D, Lerner Y, Stoye J, Steel M, Snir S. Horizontal Gene Transfer Phylogenetics: A Random Walk Approach. Molecular Biology and Evolution.
Snir, Sagi   +5 more
core   +1 more source

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti   +16 more
wiley   +1 more source

The effects of horizontal gene transfer on virulence gene sequences of enterobacterial plant pathogens.

open access: yes, 2007
The effects of horizontal gene transfer on virulence gene sequences of enterobacterial plant ...
Marianna. Naum (7950086)
core   +2 more sources

Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites

open access: yesMicrobial Cell, 2015
Horizontal gene transfer has emerged as a crucial driving force for the evolution of eukaryotes. This also includes Plasmodium falciparum and related economically and clinically relevant apicomplexan parasites, whose rather small genomes have been shaped
Carine F. Djuika   +8 more
doaj   +1 more source

A Natural System of Chromosome Transfer in Yersinia pseudotuberculosis [PDF]

open access: yes, 2012
The High Pathogenicity Island of Yersinia pseudotuberculosis IP32637 was previously shown to be horizontally transferable as part of a large chromosomal segment.
Biliana Lesic   +31 more
core   +2 more sources

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