Results 51 to 60 of about 7,506 (256)

Chromosome architecture constrains horizontal gene transfer in bacteria.

open access: yesPLoS Genetics, 2018
Despite significant frequencies of lateral gene transfer between species, higher taxonomic groups of bacteria show ecological and phenotypic cohesion. This suggests that barriers prevent panmictic dissemination of genes via lateral gene transfer. We have
Heather L Hendrickson   +3 more
doaj   +1 more source

Horizontal transfer, not duplication, drives the expansion of protein families in prokaryotes. [PDF]

open access: yesPLoS Genetics, 2011
Gene duplication followed by neo- or sub-functionalization deeply impacts the evolution of protein families and is regarded as the main source of adaptive functional novelty in eukaryotes.
Todd J Treangen, Eduardo P C Rocha
doaj   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen   +18 more
wiley   +1 more source

Horizontal Gene Transfers in Mycoplasmas (Mollicutes) [PDF]

open access: yesCurrent Issues in Molecular Biology, 2018
The class Mollicutes (trivial name "mycoplasma") is composed of wall-less bacteria with reduced genomes whose evolution was long thought to be only driven by gene losses. Recent evidences of massive horizontal gene transfer (HGT) within and across species provided a new frame to understand the successful adaptation of these minimal bacteria to a broad ...
Citti, Christine   +4 more
openaire   +4 more sources

Health‐Related Quality of Life in Rare Forms of Childhood‐Onset Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We assessed health‐related quality of life (HRQoL) in 80 children with rare hereditary spastic paraplegias using the Caregiver Priorities and Child Health Index of Life with Disabilities and clinician‐reported outcomes. HRQoL was consistently reduced, particularly in relation to motor, autonomic, and bulbar symptoms.
Henri J. D. Schmidt   +11 more
wiley   +1 more source

Updated clusters of orthologous genes for Archaea: a complex ancestor of the Archaea and the byways of horizontal gene transfer

open access: yesBiology Direct, 2012
Background Collections of Clusters of Orthologous Genes (COGs) provide indispensable tools for comparative genomic analysis, evolutionary reconstruction and functional annotation of new genomes.
Wolf Yuri I   +3 more
doaj   +1 more source

Horizontal Transfer of Domains in ssrA gene Among Enterobacteriaceae [PDF]

open access: gold, 2021
Tamilmaran Nagarajan   +3 more
openalex   +1 more source

Horizontal gene transfer: A critical view [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
It has been suggested that horizontal gene transfer (HGT) is the “essence of phylogeny.” In contrast, much data suggest that this is an exaggeration resulting in part from a reliance on inadequate methods to identify HGT events. In addition, the assumption that HGT is a ubiquitous influence throughout evolution is questionable.
C G, Kurland, B, Canback, Otto G, Berg
openaire   +2 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

nec1, a Gene Conferring a Necrogenic Phenotype, Is Conserved in Plant-Pathogenic Streptomyces spp. and Linked to a Transposase Pseudogene

open access: yesMolecular Plant-Microbe Interactions, 1998
We are investigating the genetic basis for, and evolution of, plant pathogenicity in Streptomyces spp. The plant-pathogenic species S. scabies, S. acidiscabies, and S.
Raghida A. Bukhalid   +2 more
doaj   +1 more source

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