Results 51 to 60 of about 5,178,051 (280)

Horizontal gene transfer-mediated bacterial strain variation affects host fitness in Drosophila

BMC Biology, 2021
Background How microbes affect host fitness and environmental adaptation has become a fundamental research question in evolutionary biology. To better understand the role of microbial genomic variation for host fitness, we tested for associations of ...
Yun Wang, Franz Baumdicker, Paul Schweiger, Sven Kuenzel, Fabian Staubach   +4 more
doaj   +1 more source

Mechanisms of Horizontal Gene Transfer

, 2017
Horizontal gene transfer plays important roles in the evolution of S. aureus, and indeed, a variety of virulence factors and antibiotic resistance genes are embedded in a series of mobile genetic elements.
Fabio Cafini, Morikawa, Kazuya, Veronica Medrano Romero, Kazuya Morikawa, Medrano Romero, Verónica, Cafini Barrado, Fabio   +5 more
core   +1 more source

Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms

Frontiers in Cellular and Infection Microbiology, 2012
Based on Darwin’s concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions and duplication were streaming the genomes of living organisms.
Claire eBertelli, Gilbert eGreub
doaj   +1 more source

HgtSIM: a simulator for horizontal gene transfer (HGT) in microbial communities [PDF]

PeerJ, 2017
The development and application of metagenomic approaches have provided an opportunity to study and define horizontal gene transfer (HGT) on the level of microbial communities.
Weizhi Song, Kerrin Steensen, Torsten Thomas   +2 more
doaj   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The worldwide holoparasitic Apodanthaceae confidently placed in the Cucurbitales by nuclear and mitochondrial gene trees [PDF]

, 2010
Background: Of the c. 450 families of flowering plants, only two are left “unplaced” in the most recent APG classification of angiosperms. One of these is the Apodanthaceae, a clade of c. 19 holoparasitic species in two or three genera occurring in North
Natalia Filipowicz, Renner Susanne S, Filipowicz, Natalia, Filipowicz Natalia, Susanne S Renner, Renner, Susanne S.   +5 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Horizontal gene transfer of microbial cellulases into nematode genomes is associated with functional assimilation and gene turnover

BMC Evolutionary Biology, 2011
Background Natural acquisition of novel genes from other organisms by horizontal or lateral gene transfer is well established for microorganisms. There is now growing evidence that horizontal gene transfer also plays important roles in the evolution of ...
Dieterich Christoph, Bartelmes Gabi, Schuster Lisa N, Mayer Werner E, Sommer Ralf J   +4 more
doaj   +1 more source

Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps under moderate rates of horizontal gene transfer.

PLoS Computational Biology, 2023
The horizontal transfer of genes is fundamental for the eco-evolutionary dynamics of microbial communities, such as oceanic plankton, soil, and the human microbiome.
Simone Pompei, Edoardo Bella, Joshua S Weitz, Jacopo Grilli, Marco Cosentino Lagomarsino   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source