Results 51 to 60 of about 5,536,538 (293)
Extensive horizontal gene transfer in cheese-associated bacteria
eLife, 2017 Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Kevin S Bonham +2 more
doaj +1 more source
Horizontal gene transfer-mediated bacterial strain variation affects host fitness in Drosophila
BMC Biology, 2021 Background How microbes affect host fitness and environmental adaptation has become a fundamental research question in evolutionary biology. To better understand the role of microbial genomic variation for host fitness, we tested for associations of ...
Yun Wang +4 more
doaj +1 more source
Lateral gene exchanges shape the genomes of amoeba-resisting microorganisms
Frontiers in Cellular and Infection Microbiology, 2012 Based on Darwin’s concept of the tree of life, vertical inheritance was thought to be dominant, and mutations, deletions and duplication were streaming the genomes of living organisms.
Claire eBertelli, Gilbert eGreub
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
HgtSIM: a simulator for horizontal gene transfer (HGT) in microbial communities [PDF]
PeerJ, 2017 The development and application of metagenomic approaches have provided an opportunity to study and define horizontal gene transfer (HGT) on the level of microbial communities.
Weizhi Song +2 more
doaj +2 more sources
Dimensions of Horizontal Gene Transfer in Eukaryotic Microbial Pathogens. [PDF]
, 2015 Dimensions of Horizontal Gene Transfer in Eukaryotic Microbial ...
Emile Gluck-Thaler (819798) +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]
, 2012 Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Haas, Rainer +23 more
core +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
BMC Evolutionary Biology, 2011 Background Natural acquisition of novel genes from other organisms by horizontal or lateral gene transfer is well established for microorganisms. There is now growing evidence that horizontal gene transfer also plays important roles in the evolution of ...
Dieterich Christoph +4 more
doaj +1 more source