Results 31 to 40 of about 2,860,784 (282)

Axiomatizations of quasi-polynomial functions on bounded chains [PDF]

, 2009
Two emergent properties in aggregation theory are investigated, namely horizontal maxitivity and comonotonic maxitivity (as well as their dual counterparts) which are commonly defined by means of certain functional equations.
Couceiro, Miguel, Marichal, Jean-Luc
core   +5 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

HORIZONTAL WELL DRILL-IN FLUIDS

Rudarsko-geološko-naftni Zbornik, 1998
Main objective of horizontal driling is to place a drain-hole for a long distance within the pay zone to enhance productivity or injectivity. In drilling horizontal wells, more serious problems appear than in drilling vertical wells.
Nediljka Gaurina-Međimurec
doaj  

Economic and productivity evaluation of different horizontal drilling scenarios: Middle East oil fields as case study

Journal of Petroleum Exploration and Production Technology, 2019
Development of high-density oil and gas fields presents a great challenge to the energy industry due to the low productivity of individual wells and their high drilling cost.
Abbas Khaksar Manshad, Milad Ebrahimi Dastgerdi, Jagar A. Ali, Nazir Mafakheri, Alireza Keshavarz, Stefan Iglauer, Amir H. Mohammadi   +6 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Identification of different types of kink modes in coronal loops: principles and application to TRACE results [PDF]

, 2008
We explore the possible observational signatures of different types of kink modes (horizontal and vertical oscillations in their fundamental mode and second harmonic) that may arise in coronal loops, with the aim of determining how well the individual ...
Andries, Aschwanden, Aschwanden, Berghmans, Brady, Brady, De Moortel, De Moortel, De Moortel, De Moortel, Díaz, Díaz, Edwin, Edwin, Feng, M. Selwa, McEwan, McLaughlin, Miyagoshi, Nakariakov, Nakariakov, Nakariakov, Nakariakov, Ofman, Roberts, S. K. Solanki, Schrijver, Selwa, Selwa, Selwa, T. J. Wang, Terradas, Terradas, Van Doorsselaere, Van Doorsselaere, Verwichte, Verwichte, Verwichte, Wang, Wang, Wang, Wang, Wang, Wang, Wang   +44 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Anti-collision Technology of Horizontal Well Groups in Shale Gas “Well Factory”

Shiyou jixie, 2016
With the widely applied "well factory" drilling model in shale gas development,the traditional calculation method of well trajectory distance and WdW error model can no longer meet the requirement of the wellbore anti-collision.For wireless MWD tool,the ...
Liu Maosen, Fu Jianhong, Bai Jing
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source