Results 41 to 50 of about 782,217 (265)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Formulation of New Equation to Estimate Productivity Index of Horizontal Wells

Iraqi Journal of Chemical and Petroleum Engineering, 2014
Significant advances in horizontal well drilling technology have been made in recent years. The conventional productivity equations for single phase flowing at steady state conditions have been used and solved using Microsoft Excel for various reservoir ...
Ghanim M. Farman, Maha Raouf Abdulamir
doaj  

Modeling of Inflow Well Performance of Multilateral Wells: Employing the Concept of Well Interference and the Joshi's Expression [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2011
The use of multilateral well is becoming an emerging method to improve oil recovery efficiently and to drain reservoirs more efficacious. By developing drilling technology, completing the oil wells as multilateral wells become more interesting especially
Seyed Reza Shadizadeh, Mohammad Ali Kargarpour, Mansoor Zoveidavianpoor   +2 more
doaj  

Horizontal well fracturing technology for reservoirs with low permeability

Petroleum Exploration and Development, 2009
The horizontal well stress distribution and the rock failure criterion constitute a fracture initiation mathematical model, which was solved by the iteration method.
Cai Wenbin, Li Zhaomin, Zhang Xialin, Zhang Bo, Zhang Qi   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Application of Long Lateral Section Horizontal Well Drilling Technology in Well ZC1

Shiyou jixie, 2017
The Well ZC1 has a long horizontal section with the target reservoir of Chang 6. To address the issues like shallow buried depth of Chang 6 reservoir, long horizontal section and open hole section, difficulty in wellbore cleaning and stability of ...
Tang Honglin, Yang Chunxu, Zhong Junlin, Yu Jianqing   +3 more
doaj  

ASPECTS OF OPTIMIZATION OF DRILLING DIRECTIONAL WELLS

Известия высших учебных заведений: Нефть и газ, 2017
Analysis of the Russian and foreign expertisein optimizing the drilling process suggeststhe need to develop new methods for solving the problems associated with the process of drilling directional wells, in order to prevent possible complications and on ...
V. G. Kuznetsov, E. G. Grechin, D. A. Nikiforov, E. N. Savin   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source