Results 101 to 110 of about 377,752 (312)

Menopause and menopausal hormone therapy in women: cardiovascular benefits and risks

Revista Colombiana de Cardiología, 2018
The last decade has brought many challenges and uncertainties regarding the use of menopausal hormone therapy in women. Two early key studies, the Heart and Estrogen/Progestin Replacement Study (HERS) and the Women's Health Initiative (WHI) failed to ...
Anna Svatikova, Sharonne N. Hayes
doaj   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
wiley   +1 more source

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]

, 2013
Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during
Abdel-Fatah, TMA, Agarwal, D, Albarakati, N, Ball, G, Bowell, L, Chan, S, Ellis, IO, Hawkes, C, Madhusudan, S, Moseley, P   +9 more
core   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

A systematic review of the effectiveness of docetaxel and mitoxantrone for the treatment of metastatic hormone-refractory prostate cancer [PDF]

, 2006
A systematic review was performed to evaluate the clinical effectiveness of docetaxel in combination with prednisolone (docetaxel is licensed in the UK for use in combination with prednisone or prednisolone for the treatment of patients with metastatic ...
A Birtle, DP Petrylak, DP Petrylak, DS Ernst, E Fenwick, G Norman, IF Tannock, IF Tannock, K Light, M Egger, MA Eisenberger, PW Kantoff, R Collins, R Riemsma, R Trowman, S Oudard, S Palmer, SR Muthuramalingam, W Berry, W Kelly   +19 more
core   +2 more sources

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Past, present, and future of hormonal therapy in recurrent endometrial cancer

International Journal of Women's Health, 2014
Matthew J Carlson, Kristina W Thiel, Kimberly K LeslieDepartment of Obstetrics and Gynecology, University of Iowa, Iowa City, IA, USAAbstract: Endometrial cancer is a heterogeneous disease.
Carlson MJ, Thiel KW, Leslie KK
doaj  

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Terapia hormonal de reemplazo y cáncer Hormonal replacement therapy and cancer

Revista Colombiana de Obstetricia y Ginecología, 2004
El temor al riesgo de algunos tipos de cáncer en especial el mamario relacionado con el uso de la terapia hormonal de reemplazo ha sido a lo largo de las últimas tres décadas un tema de controversia e investigación permanente.
Gilberto Martínez Morales
doaj  

Menopause in women with chronic immunosuppressive treatment – how to help those patients

Menopause Review, 2016
Women after organ transplantation with chronic immunosuppressive therapy or after bone marrow transplantation without such therapy are a growing group of patients.
Anna Cyganek, Bronisława Pietrzak, Mirosław Wielgoś, Barbara Grzechocińska   +3 more
doaj   +1 more source