Results 211 to 220 of about 1,323,336 (317)

Follikelstimulierendes-Hormon-Releasing-Hormon [PDF]

, 2019
openaire   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source

Relationship between menopausal hormone therapy and incidence risk of breast cancer: systematic review and meta-analysis. [PDF]

Ann Med
Wu Q, Shen L, Hu S, Yang R, Wang Y, Xue D, Sun Y, Ma H, Dai Z.   +8 more
europepmc   +1 more source

Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study [PDF]

Carey E. Gleason, N. Maritza Dowling, Firat Kara, Taryn T. James, Hector Salazar, Carola Ferrer Simó, S. Mitchell Harman, JoAnn E. Manson, Dustin B. Hammers, Frederick Naftolin, Lubna Pal, Virginia M. Miller, Marcelle I. Cedars, Rogerio A. Løbo, Michael Malek‐Ahmadi, Kejal Kantarci   +15 more
openalex   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Associations of surgical menopause and hormone replacement therapy with meningioma development. [PDF]

J Neurooncol
Zeng W, Jedwood C, Chung R, Cote DJ, Dallas J, Briggs RG, Omotosho YB, Carmichael J, Zada G.   +8 more
europepmc   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

The Author of the Studies Cited in the above Letter Responds

The International Journal of Biological Markers, 2006
G. Secreto
doaj   +1 more source

Sex and age specific hormonal patterns in healthy Chinese individuals: a cross-sectional study of reproductive hormones. [PDF]

Sci Rep
Ahamed Y, Ashraf SB, Dauty RT, Baral S, Hossain M, Chen J, Wu LC, Sun W.   +7 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source