Results 121 to 130 of about 136,105 (353)

Species Selectivity of Nonpeptide Antagonists of the Gonadotropinreleasing Hormone Receptor Is Determined by Residues in Extracellular Loops II and III and the Amino Terminus [PDF]

, 2004
Greg J. Reinhart, Qiu Xie, Xin-Jun Liu, Yunfei Zhu, Jun Fan, Chen Chen, R. Scott Struthers   +6 more
openalex   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Relugolix: A new kid on the block among gonadotrophin-releasing hormone antagonists. [PDF]

Arab J Urol, 2021
Fragkoulis C, Glykas I, Dellis A, Mitsogiannis I, Papatsoris A.   +4 more
europepmc   +1 more source

Gonadotrophin-releasing hormone antagonists inhibit sperm binding to the human zona pellucida [PDF]

, 1999
Patricio Morales, Bredford Kerr, Carolina A. Oliva, Eduardo Pizarro, Milene Kong   +4 more
openalex   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Follicle-Stimulating Hormone Exacerbates Cardiovascular Disease in the Presence of Low or Castrate Testosterone Levels

JACC: Basic to Translational Science
Summary: Low testosterone (T), common in aging men, associates with cardiovascular disease. We investigated whether follicle-stimulating hormone (FSH), which is affected by T, modulates the cardiovascular effects associated with low T or castration. FSHβ−
Wilhelmina C.M. Duivenvoorden, MSc PhD, David Margel, MD, PhD, Vishal Subramony Gayathri, MSc, Emmanuelle Duceppe, MD, PhD, Sadiya Yousef, BSc, Magda Naeim, PhD, Mohammad Khajehei, MSc, Sarah Hopmans, MSc, Snezana Popovic, MD, Yaara Ber, MSc, Diane Heels-Ansdell, MSc, Philip J. Devereaux, MD, PhD, Jehonathan H. Pinthus, MD, PhD   +12 more
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Beyond depression and anxiety; a systematic review about the role of corticotropin-releasing hormone antagonists in diseases of the pelvic and abdominal organs. [PDF]

PLoS One, 2022
Pagán-Busigó JE, López-Carrasquillo J, Appleyard CB, Torres-Reverón A.   +3 more
europepmc   +1 more source

Human Growth Hormone Antagonist (G120R) Delivered by a Murine Yolk Sac Cell‐Derived Mini‐Organ Decreases the Growth Rate of Mice [PDF]

, 1997
Yanzhang Wei, Jinhua Li, Wen Y. Chen, Thomas E. Wagner   +3 more
openalex   +1 more source

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source