Results 231 to 240 of about 561,014 (300)

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Increased Serum Levels of Dickkopf-1 and Sclerostin as WNT Signaling Pathway Inhibitors in Celiac Disease Patients. [PDF]

Immun Inflamm Dis
Al-Ani MNT, Yahya SKT, Dastorani M, Mirkarimi H, Besharat S, Jazi MS.   +5 more
europepmc   +1 more source

Mechanisms for Mineralocorticoid-Driven Age-Related Hypertension: Potential Therapeutic Role of Mineralocorticoid Receptor Antagonists and Aldosterone Synthase Inhibitors. [PDF]

Circ Res
Golec S, Vaidya A, Pitt B, Jaffe IZ.
europepmc   +1 more source

Recent Advances (2020-2025) in Estrogen and ER-Positive Breast Cancer: Receptor Signaling, Tumor Microenvironment, Endocrine Therapy Resistance and Innovative Treatment Strategies-A Comprehensive Review. [PDF]

Cancer Manag Res
Zhao J, Li D, Yang S, Ma X.
europepmc   +1 more source

A novel approach to treating Endometriosis-Related Repeated IVF failures- insights from single case report. [PDF]

Reprod Biol Endocrinol
Orvieto R.
europepmc   +1 more source

Indian Delphi consensus on cardiovascular risk mitigation in prostate cancer management. [PDF]

Front Oncol
Bakshi G, Lyon A, Joshi A, Agarwala V, Raghunath SK, Addla SK, Taneja R, Mandani A, Kashyapi B, Bhargava S, Sharma R, Agrawal V, Nagar R, Srivathsan R, Patel K, Patel R, Shah H, Lai A, Mukherjee A, Pandey S, Rajput A.   +20 more
europepmc   +1 more source

Views on outpatient paracentesis and GnRH antagonists for ovarian hyperstimulation syndrome: a qualitative study of patients and healthcare professionals.

Health Technol Assess
Lumley E, O'Cathain A, Ridsdale K, Drabble S, White D, Pye C, Wright J, Drakeley A, Cheong Y, Mathur R, Barr A, Metwally M, STOP-OHSS Study Group.   +12 more
europepmc   +1 more source

Calcium Antagonists and Hormone Release

Clinical Science, 1984
Introduction: Calcium (Ca2+) has been aptly entitled the ‘universal provocateur’ [1] in recognition of its many indispensable metabolic actions. The class of drugs popularly known as calcium antagonists (calcium slow channel blockers) provokes a variety of pharmacological effects and these drugs are useful as probes of calcium-dependent mechanisms. One
Millar, J. A., Struthers, A. D.
openaire   +4 more sources