Results 131 to 140 of about 5,954,376 (381)

ARCHES: A Randomized, Phase III Study of Androgen Deprivation Therapy With Enzalutamide or Placebo in Men With Metastatic Hormone-Sensitive Prostate Cancer

open access: yesJournal of Clinical Oncology, 2019
PURPOSE Enzalutamide, a potent androgen-receptor inhibitor, has demonstrated significant benefits in metastatic and nonmetastatic castration-resistant prostate cancer.
A. Armstrong   +14 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Ten-year adjuvant hormone therapy for breast cancer: the pros and cons (a review of literature)

open access: yesОпухоли женской репродуктивной системы, 2014
Tamoxifen is one of the basic drugs of adjuvant hormone therapy in patients with hormone-dependent breast tumors. The purpose of this paper is to analyze the results of randomized trials of long-term adjuvant hormone therapy for breast cancer.
S. M. Portnoy, T. A. Shendrikova
doaj   +1 more source

Hormonal therapy in cancer of the breast.VI. Effect of ACTH and cortisone on clinical course and hormonal excretion [PDF]

open access: bronze, 1954
Albert Segaloff   +4 more
openalex   +1 more source

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

open access: yesAdvanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault   +7 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Menopausal hormone therapy for the management of osteoporosis.

open access: yesBest practice & research. Clinical endocrinology & metabolism, 2021
A. Gosset   +2 more
semanticscholar   +1 more source

Growth Hormone Therapy in Adults with Prader-Willi Syndrome

open access: yesDiseases, 2015
Prader-Willi syndrome (PWS) is characterized by hyperphagia, obesity if food intake is not strictly controlled, abnormal body composition with decreased lean body mass and increased fat mass, decreased basal metabolic rate, short stature, low muscle tone,
Karen S. Vogt, Jill E. Emerick
doaj   +1 more source

Hormonal Therapies: Progesterone [PDF]

open access: yesNeurotherapeutics, 2009
Seizures do not occur randomly in the majority of people with epilepsy. They tend to cluster. Seizure clusters, in turn, commonly occur with a temporal rhythmicity that shows a readily identifiable and predictable periodicity. When the periodicity of seizure exacerbation in women conforms to that of the menstrual cycle, it is commonly known as ...
openaire   +3 more sources

Home - About - Disclaimer - Privacy