Bioidentical Hormone Therapy [PDF]
The change in hormonal milieu associated with perimenopause and menopause can lead to a variety of symptoms that can affect a woman's quality of life. Postmenopausal hormone therapy (HT) is an effective, well-tolerated treatment for these symptoms. However, combined HT consisting of conjugated equine estrogen and medroxyprogesterone acetate has been ...
Marcia G. Ko+2 more
openaire +3 more sources
Body Dissatisfaction and Mental Health Outcomes of Youth on Gender-Affirming Hormone Therapy
This study examines changes in youth body dissatisfaction and mental health after gender-affirming hormone therapy and explores the impact of demographic and treatment variables.
L. Kuper+4 more
semanticscholar +1 more source
Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
We provide an evidence base and guidance for the use of menopausal hormone therapy (MHT) for the maintenance of skeletal health and prevention of future fractures in recently menopausal women.
S. Rozenberg+23 more
semanticscholar +1 more source
Menopausal hormone therapy: oncological risks [PDF]
The review article presents an analysis of the literature over the past 10 years on the relationship of menopausal hormone therapy and the risks of developing malignant diseases in women, including risk factors, such as mutations in the BRCA1/2 genes ...
Ekaterina V. Musina, Igor Yu. Kogan
doaj +1 more source
Progestogens in menopausal hormone therapy
Progestogens share one common effect: the ability to convert proliferative endometrium to its secretory form. In contrast, their biological activity is varied, depending on the chemical structure, pharmacokinetics, receptor affinity and different potency
Małgorzata Bińkowska, Jarosław Woroń
doaj +1 more source
Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study [PDF]
Combined oral contraceptives,oral hormone replacement therapy and thrombophilias are recognised risk factors for venous thromboembolism in women.The objective of this study was to assess the risk of thromboembolism among women with thrombophilia who are ...
Brenkel, I.+10 more
core +1 more source
BACKGROUND Transgender individuals receiving masculinising or feminising gender-affirming hormone therapy with testosterone or estradiol respectively, are at increased risk of adverse cardiovascular outcomes, including myocardial infarction and stroke ...
Cassandra Spanos+3 more
semanticscholar +1 more source
Erythema nodosum as a result of estrogen patch therapy for prostate cancer: a case report. [PDF]
© 2015 Coyle et al.Introduction: Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue.
Abel, P+3 more
core +2 more sources
The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor [PDF]
Prostate cancer is the second most common male malignancy in the western world an increasing incidence in an ageing population. Treatment of advanced prostate cancer relies on androgen deprivation.
Bakin RE+7 more
core +1 more source
Cryopreservation of Human Hepatocytes Alters the Mitochondrial Respiratory Chain Complex 1
Transplantation of human hepatocytes has recently been demonstrated as a safe alternative to partially correct liver inborn errors of metabolism. Cryopreservation remains the most appropriate way of cell banking. However, mitochondrial-mediated apoptosis
Xavier Stéphenne+6 more
doaj +1 more source