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Recommended Hormone Therapy in Menopause: Concepts, Controversies and Approach to Treatment.
Hormone therapy (HT) is an effective treatment for menopausal symptoms, including vasomotor symptoms and genitourinary syndrome of menopause. Randomized trials also demonstrate positive effects on bone health, and age-stratified analyses indicate more ...
V. A. Flores, L. Pal, Joann E Manson
semanticscholar +1 more source
CONTEXT This mini-review provides an overview of menopausal hormone therapy (HT) and cardiovascular disease (CVD) risk, with a focus on the role of hormone formulation, dose, and route of delivery. METHODS This summary is based on authors' knowledge in
C. Shufelt, J. Manson
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Hormone therapy for ovarian cancer: Emphasis on mechanisms and applications
Ovarian cancer (OC) remains the leading cause of mortality due to gynecological malignancies. Epidemiological studies have demonstrated that steroid hormones released from the hypothalamic-pituitary-ovarian axis can play a role in stimulating or ...
Hongyi Li +4 more
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Body Dissatisfaction and Mental Health Outcomes of Youth on Gender-Affirming Hormone Therapy
This study examines changes in youth body dissatisfaction and mental health after gender-affirming hormone therapy and explores the impact of demographic and treatment variables.
L. Kuper +4 more
semanticscholar +1 more source
Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
We provide an evidence base and guidance for the use of menopausal hormone therapy (MHT) for the maintenance of skeletal health and prevention of future fractures in recently menopausal women.
S. Rozenberg +23 more
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Progestogens in menopausal hormone therapy
Progestogens share one common effect: the ability to convert proliferative endometrium to its secretory form. In contrast, their biological activity is varied, depending on the chemical structure, pharmacokinetics, receptor affinity and different potency
Małgorzata Bińkowska, Jarosław Woroń
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Menopausal hormone therapy: oncological risks [PDF]
The review article presents an analysis of the literature over the past 10 years on the relationship of menopausal hormone therapy and the risks of developing malignant diseases in women, including risk factors, such as mutations in the BRCA1/2 genes ...
Ekaterina V. Musina, Igor Yu. Kogan
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Erythema nodosum as a result of estrogen patch therapy for prostate cancer: a case report. [PDF]
© 2015 Coyle et al.Introduction: Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue.
Abel, P +3 more
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The androgen receptor and signal-transduction pathways in hormone-refractory prostate cancer. Part 1: modifications to the androgen receptor [PDF]
Prostate cancer is the second most common male malignancy in the western world an increasing incidence in an ageing population. Treatment of advanced prostate cancer relies on androgen deprivation.
Bakin RE +7 more
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External radiotherapy of thyroid cancer [PDF]
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
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