Menopause hormone therapy: latest developments and clinical practice
Menopause hormone therapy (MHT) is the most efficient treatment for symptoms of acute climacteric syndrome and for efficient prevention of long-term estrogen deficiency. Vaginal administration of low doses of estrogen is a therapy of choice for treatment
Tomas Fait
doaj +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
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Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L. +11 more
core +1 more source
Which patients with prostate cancer are actually candidates for hormone therapy?
In this article, we will try to address the following aspects: which factors are responsible of the introduction of new candidates for hormone therapy in prostate cancer, who are actually candidates for hormone therapy, classifying them on the basis of ...
Alessandro Sciarra +5 more
doaj +1 more source
Reference Profile Correlation Reveals Estrogen-like Trancriptional Activity of Curcumin [PDF]
Background: Several secondary metabolites from herbal nutrient products act as weak estrogens (phytoestrogens), competing with endogenous estrogen for binding to the estrogen receptors and inhibiting steroid converting enzymes.
Albini, Adriana +9 more
core +1 more source
BackgroundEven after the Women's Health Initiative (WHI) found that the risks of menopausal hormone therapy (hormone therapy) outweighed benefit for asymptomatic women, about half of gynecologists in the United States continued to believe that hormones ...
Adriane Fugh-Berman +4 more
doaj +1 more source
Hormonal replacement therapy, prothrombotic mutations and the risk of venous thrombosis [PDF]
Hormone replacement therapy (HRT) increases the risk of venous thrombosis. We investigated whether this risk is affected by carriership of hereditary prothrombotic abnormalities.
A. Rumley +26 more
core +1 more source
KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function [PDF]
Estrogen receptor alpha (ER alpha) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas.
Abdel-Wahab, Omar +13 more
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Intentional and non-intentional non-adherence to medication amongst breast cancer patients [PDF]
This study aimed to investigate the prevalence of and factors associated with non-adherence to medication amongst a sample of breast cancer patients. 131 women with stable disease were interviewed and completed standardised psychological measures. 55% of
Demissie +17 more
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Background and objectives: To find out the response to growth hormone therapy among growth hormone deficiency patients with different causes and to find out the role of insulin-like growth factor one in monitoring response.
Kawes Omer Zangana +2 more
doaj +1 more source

