Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
wiley +1 more source
Phenotypic Traits, Hormonal Distribution, and Metabolite Profiling of <i>Isatis indigotica</i> Seeds from 21 Samples in China: A Traditional Chinese Medicinal Herb. [PDF]
Wang L+11 more
europepmc +1 more source
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu+38 more
wiley +1 more source
Melasma secondary to drugs: a real-world pharmacovigilance study of the FDA adverse event reporting system (FAERS). [PDF]
Qu Y+5 more
europepmc +1 more source
HORMONAL INFLUENCES ON MAMMARY TUMORS OF THE RAT [PDF]
Charles Huggins+2 more
openalex +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
Listeria monocytogenes infection in intestinal epithelial Caco-2 cells with exposure to progesterone and estradiol-17beta. [PDF]
Hugon AM, Golos TG.
europepmc +1 more source
RECIPROCAL RELATION BETWEEN THE HYPOPHYSIS AND ADRENALS IN FETAL RATS: EFFECTS OF UNILATERAL ADRENALECTOMY AND OF IMPLANTED CORTISONE, DOCA AND SEX HORMONES123 [PDF]
Ralph L. Kitchell, L. J. Wells
openalex +1 more source
The GhWL1‐GhH1‐GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology
This study identified GhWL1 as a key gene involved in regulating leaf development through analysis of a T‐DNA insertion mutant. The GhWL1‐GhH1 complex is shown to positively regulate GhGA2OX1 by directly binding to its promoter, thereby establishing the GhWL1‐GhH1‐GhGA2OX1 module as a critical pathway in leaf development.
Jingjing Zhan+12 more
wiley +1 more source
Ovarian vascular aging: a hidden driver of mid-age female fertility decline. [PDF]
Wang G, Yang R, Zhang H.
europepmc +1 more source