Results 51 to 60 of about 696,235 (313)
Interplay between androgen and CXCR4 chemokine signaling in myelin repair
Acta Neuropathologica CommunicationsIn men, reduced levels of testosterone are associated with the prevalence and progression of multiple sclerosis (MS), a chronic and disabling demyelinating disorder. Testosterone has been shown to promote myelin repair.
Narimène Asbelaoui +7 more
doaj +1 more source
Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma
BMC Cancer, 2017 Background Germline mutations in genes encoding subunits of succinate dehydrogenase (SDH) are associated with the development of pheochromocytoma (PC) and/or paraganglioma (PGL). As assembly factors have been identified as playing a role in maturation of
Trisha Dwight +10 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
, 2012 Local hormones or autocoids are chemical mediators that are secreted by one group of cells to affect the function of other nearby cells. This eChapter covers a diverse range of these mediators, their physiological effects, pathological implications and ...
Hart, Joaane L.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Cell Death and Disease, 2021 The altered homeostasis of mitochondria-associated endoplasmic reticulum (ER) membranes (MAM) was closely associated with the pathological process of nervous system diseases and insulin resistance.
Mei Xue +9 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
, 2018 The nervous and endocrine systems are 2 important related systems. Thyroid hormones, in particular, bind to the nuclear receptors of neuronal and glial cells, which affects migration, myelination, and synaptogenesis, and contributes to the development ...
Sıbel Guldıken +2 more
core +1 more source
Molecular mechanisms involved in the cold tolerance response and regulation of fruits and vegetables
Horticulture AdvancesFresh fruits and vegetables are critical sources of essential nutrients and natural pigments, playing a significant role in human health. However, low-temperature stress represents a major abiotic factor influencing plant growth and development. Exposure
Sijie Wang +6 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source