Results 101 to 110 of about 721,045 (358)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

An investigation into the effect of floor colour on the behaviour of the horse [PDF]

, 2006
Adverse reactions of the domestic horse to environmental stimuli can be problematic in training and management. Hesitation and alarm reactions to visual features of the ground can occur in both ridden work and when handling horses.
Cassaday, HJ, Hall, CA
core   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Comparative proteomic profiling of the ovine and human PBMC inflammatory response

Scientific Reports
Understanding the cellular and molecular mechanisms of inflammation requires robust animal models. Sheep are commonly used in immune-related studies, yet the validity of sheep as animal models for immune and inflammatory diseases remains to be ...
A. Elkhamary, I. Gerner, A. Bileck, G. L. Oreff, C. Gerner, F. Jenner   +5 more
doaj   +1 more source

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation

Advanced Healthcare Materials, EarlyView.
Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillation, we present a powerful method to accurately mimic the ultrastructure of Collagen with polycaprolactone, enabling the one‐step fabrication of three ...
Zan Lamberger, Vivien Priebe, Philipp Stahlhut, Kristina Andelovic, Girish Pattappa, Denitsa Docheva, Sven Heilig, Heike M. Hermanns, Taufiq Ahmad, Jürgen Groll, Gregor Lang, Matthias Ryma   +11 more
wiley   +1 more source

Frequency of shedding of respiratory pathogens in horses recently imported to the United States. [PDF]

, 2018
BackgroundImported horses that have undergone recent long distance transport might represent a serious risk for spreading infectious respiratory pathogens into populations of horses.ObjectiveTo investigate the frequency of shedding of respiratory ...
Boyle, Browne, Dunowska, Dunowska, Gnann, Goor, Legrand, Lindahl, Mapes, Marenzoni, Mason, Ohmura, Padalino, Pusterla, Pusterla, Pusterla, Rushton, Schrader, Sevinga, Smyth, Smyth, Stull, Torfason, Traub-Dargatz, Vander Werf, Williams   +25 more
core   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

Equine recurrent uveitis - A spontaneous horse model of uveitis [PDF]

, 2008
Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis.
Altmann, Frank, Amann, Barbara, Deeg, Cornelia A., Hauck, Stefanie M., Pompetzki, Dirk, Raith, Albert, Schmalzl, Thomas, Stangassinger, Manfred, Ueffing, Marius   +8 more
core   +1 more source

A prospective study on the microbiological examination of secretions from the paranasal sinuses in horses in health and disease

Acta Veterinaria Scandinavica, 2018
Background Diagnostics in equine sinusitis can be challenging and often require a combination of different imaging tools to ascertain its underlying aetiology.
Hauke Gergeleit, Jutta Verspohl, Judith Rohde, Karl Rohn, Bernhard Ohnesorge, Astrid Bienert-Zeit   +5 more
doaj   +1 more source