Results 81 to 90 of about 217,253 (300)

The ABCA1 blocking agent probucol decreases capacitation in ejaculated dog spermatozoa

open access: yesActa Veterinaria Scandinavica, 2020
Background The ATP binding cassette (ABC) transporters participate in the cholesterol and phospholipid transport within and through cell membranes of many cells including spermatozoa. Cholesterol efflux is important for capacitation of spermatozoa. ABCA1
Sabine Schäfer-Somi, Sven Budik
doaj   +1 more source

Episode 107: Horses and War with Donna Landry

open access: yes, 2019
In this episode of Knowing Animals we are joined by Prof. Donna Landry. Donna is in the School of English, Rutherford College, at the University of Kent, UK. We discuss her book chapter ‘Horses at Waterloo, 1815’ which will appear in the forthcoming book
Landry, Donna, O'Sullivan, Siobhan
core   +1 more source

Endocrine and haemodynamic investigations of normal and laminitic horses. [PDF]

open access: yes, 1996
The historical and evolutionary perspectives of equine laminitis were placed in a contemporary context of hippology. A survey revealed 3% of the equine population in the UK to be affected by laminitis.
Hinckley, K.A., Hinckley, Karen Ann
core   +4 more sources

Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis

open access: yesAdvanced Science, EarlyView.
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko   +8 more
wiley   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

open access: yesAdvanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian   +12 more
wiley   +1 more source

The changing importance of horses within the Celtic society [PDF]

open access: yes, 2011
Based on archaeological evidence, horses have been utilized, initially as a food source, by humans since the Upper Paleolithic. It was not until ca. 2500 B.C. when horses in Europe were domesticated for draft animals and other purposes.
Jennings, Lisa M.
core  

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

open access: yesAdvanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale   +23 more
wiley   +1 more source

[News Clip: Loose Horses]

open access: yes, 1959
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about three horses loose in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

Comparative proteomic profiling of the ovine and human PBMC inflammatory response

open access: yesScientific Reports
Understanding the cellular and molecular mechanisms of inflammation requires robust animal models. Sheep are commonly used in immune-related studies, yet the validity of sheep as animal models for immune and inflammatory diseases remains to be ...
A. Elkhamary   +5 more
doaj   +1 more source

Species-specific inflammatory responses of chondrocytes: Toward evidence-based model selection in OA research

open access: yesiScience
Summary: To inform evidence-based osteoarthritis model selection, this study compares inflammatory responses of articular chondrocytes from six species (human, horse, sheep, rabbit, rat, and mouse) under standardized IL-1β and TNF-α stimulation in 2D and
Angkana Kidtiwong   +6 more
doaj   +1 more source

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