Results 71 to 80 of about 210,012 (299)

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Case Report: α1-antitrypsin deficiency causing persistent pleural effusion and multilobar alveolar emphysema in a young dog

Frontiers in Veterinary Science
Alpha-1 antitrypsin deficiency (A1ATD) is a rare genetic condition in both humans and animals, caused by mutations in the SERPINA1 gene that lead to reduced or absent production of alpha-1 antitrypsin (A1AT).
Pavlos G. Doulidis, Carolina Frizzo-Ramos, Christof A. Bertram, Olivia M. Grünzweil, Sibylle M. Kneissl, Brigitte Degasperi, Reinhard A. Hirt, Iwan A. Burgener, Nicole Luckschander-Zeller   +8 more
doaj   +1 more source

Accurate determination of phenotypic information from historic thoroughbred horses by single base extension [PDF]

, 2010
Historic DNA have the potential to identify phenotypic information otherwise invisible in the historical, archaeological and palaeontological record. In order to determine whether a single nucleotide polymorphism typing protocol based on single based ...
Michael G Campana, Ceiridwen J. Edwards, Edwards Ceiridwen J., Matthew M. Binns, Ceiridwen J Edwards, Frauke Stock, Murphy, A., Cambridge, Campana, M G, Edwards, C J, Binns, Matthew M., Mim A. Bower, Binns Matthew M., Fleischer, Robert C., Graeme W. W. Barker, C. Mark Whitten, Stock Frauke, Binns, M M, Graeme W W Barker, Campana, M., Barker, Graeme W. W., Campana Michael G., Bower Mim A., Barker Graeme W. W., Campana, Michael G., Trinity College Dublin, Bower, Mim A., Bower, M., Barker, G W W, Mim A Bower, Barker, G., Murphy Angela M., Murphy, A M, Michael G. Campana, Edwards, C., C Mark Whitten, Stock, Frauke, Bower, M A, Stock, F., Whitten, C. Mark, Binns, M., Whitten, C M, Angela M Murphy, Angela M. Murphy, Matthew M Binns, Whitten C. Mark, Whitten, C., Edwards, Ceiridwen J., Stock, F, Murphy, Angela M.   +49 more
core   +2 more sources

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Sisältömarkkinointisuunnitelman luominen KM Horses Oy:lle [PDF]

, 2022
Kulutuskäyttäytyminen on muuttunut asiakkaiden etsiessä itse tietoa yrityksistä ja yrityksien tuotteista digitalisaation avulla. Myös mielikuva yrityksestä on nykypäivänä entistä tärkeämpi asiakkaan vertaillessa yrityksiä.
Pohjanharju, Jenni
core  

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

The ABCA1 blocking agent probucol decreases capacitation in ejaculated dog spermatozoa

Acta Veterinaria Scandinavica, 2020
Background The ATP binding cassette (ABC) transporters participate in the cholesterol and phospholipid transport within and through cell membranes of many cells including spermatozoa. Cholesterol efflux is important for capacitation of spermatozoa. ABCA1
Sabine Schäfer-Somi, Sven Budik
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source