Results 41 to 50 of about 582,561 (305)

Point-prevalence of Hospital-Acquired Infections at Vietnamese Urban Hospital

Online Journal of Health & Allied Sciences, 2022
Background: This study aimed to evaluate the prevalence of hospital-acquired infections among inpatients at a public hospital in Vietnam, and analyze the factors associated with this condition.
Tran Thanh Tu, Pham Minh Khue, Doan Ngoc Hai, Dao Quang Minh, Nguyen Thi Dung   +4 more
doaj  

Hospital-Acquired Infections Caused by Carbapenem-Resistant Enterobacteriaceae: An Observational Study

Microorganisms, 2023
Worldwide, hospital-acquired infections (HAIs) are continuously rising within healthcare settings, leading to high mortality and morbidity rates. Many hospitals have reported the spread of carbapenemases globally, specifically within the E.
Hamzah J. Aldali, Azra Khan, Abdullah A. Alshehri, Jehad A. Aldali, Sultan Ayoub Meo, Ali Hindi, Emadeldin M. Elsokkary   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Processes of care in surgical patients who died with hospital-acquired infections in Australian hospitals

, 2018
Background Infection may complicate surgical patients' hospital admission. The effect of hospital-acquired infections (HAIs) on processes of care among surgical patients who died is unknown.
Rey-Conde, T, J.L. Veerman, Kruger, P, T. Rey-Conde, G.J. Maddern, Maddern, GJ, W.J. Babidge, Wysocki, AP, Babidge, WJ, P. Kruger, North, JB, Allen, J, A.P. Wysocki, R.S. Ware, Veerman, JL, J.B. North, J. Allen, Ware, RS   +17 more
core   +1 more source

The symptoms and interval of Omicron SARS-CoV-2 reinfection among healthcare workers in a hospital of Southern China: a cross-sectional study

BMC Infectious Diseases
Background The prevalence and distinction between first Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and reinfection with the Omicron variant among healthcare workers (HCWs) remain unclear.
Xiaoju Ma, Zheng Wang, Youpeng Chen, Zhanjie Li   +3 more
doaj   +1 more source

Nosocomial acquisition of influenza is associated with significant morbidity and mortality: Results of a prospective observational study

Journal of Infection and Public Health, 2022
Background: Nosocomial acquisition of influenza is known to occur but the risk after exposure to a known case and the outcomes after acquisition are poorly defined.
L.B. Snell, J.P. Vink, N.Q. Verlander, S. Miah, A. Lackenby, D. Williams, H. Mitchell, C. Beviz, M. Kabia, E. Cunningham, R. Batra, J.D. Edgeworth, M. Zambon, G. Nebbia   +13 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Results from the Scottish national HAI prevalence survey

, 2008
A national point prevalence survey was undertaken over the period of one calendar year in Scotland from October 2005 to October 2006. The prevalence of healthcare-associated infection (HAI) was 9.5% in acute hospitals and 7.3% in non-acute hospitals. The
Reilly, J., Robertson, C., Allardice, G., The Scottish Executive Health Department HAI Task Force (Funder), Coubrough, S., Reilly, Jacqui; id_orcid, Walker, A., Allardice, G.A., Stewart, S., Allardice, G.M., , The Scottish Executive Health Department HAI Task Force (Funder), Noone, A.   +11 more
core   +1 more source

How do hospital professionals involved in a randomised controlled trial perceive the value of genotyping vs. PCR-ribotyping for control of hospital acquired C. difficile infections? [PDF]

, 2014
Background: Despite scientific advances in typing of C. difficile strains very little is known about how hospital staff use typing results during periods of increased incidence (PIIs). This qualitative study, undertaken alongside a randomised controlled
Peter M Hawkey, Hawkey, Peter M., Szczepura, Ala, Parsons, Helen, Katherine Hardy, Susan Manzoor, Gossain, Savita, Savita Gossain, Hardy, K. (Katherine), Stallard, Nigel, Nigel Stallard, Manzoor, Susan, Ala Szczepura, Hardy, Katherine, Helen Parsons, Hawkey, P. M. (Peter M.), Szczepura, Ala; id_orcid   +16 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source