Results 51 to 60 of about 4,912,407 (281)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Hand Hygiene Compliance among Personnel of Taleghani Hospital in Tabriz [PDF]

Taṣvīr-i salāmat, 2016
Background and Objectives: Hand hygiene is considered the most effective measure to prevent and control hospital infections. This study aimed to determine the level of hand hygiene compliance and to compare the level of hand hygiene compliance after ...
Nesa Kavakebi, Parvin Aliabadi, khadijeh Pazani, Nayyer Aslnejad-Moghaddami, Zohreh Tahmasbi, Parvin Abbasian, Fateme Safari, Leila Rastgar-Farajzadeh   +7 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Correlation between class 1 integron of Escherichia coli and multidrug resistance in lower respiratory tract infection

Journal of Infection in Developing Countries, 2017
Introduction: Class 1 integrons are mobile genetic elements considered to be responsible for the transfer of multidrug resistance. This study aimed to investigate the distribution of type 1 integrons in multidrug-resistantEscherichiacolifrom hospital ...
Yu Wang, Bingbing Kong, Wenping Yang, Xin Zhao   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Artificial intelligence in infection prevention and control education: toward intelligent, real-time clinical learning systems

Frontiers in Public Health
Artificial intelligence (AI) is increasingly being explored in infection prevention and control (IPC) education as a means of addressing limitations of conventional training, including limited scalability, delayed feedback, and subjective competency ...
Yu-long Cao, Na Liu, Fang Wang, Jiao Shan, Xiao-yuan Bao, Meng Jin, Wei Huai, Yi-cheng Jin, Yi-xi Jin, Zhi-ning Zhang, Ji-qiu Kuang   +10 more
doaj   +1 more source

A retrospective study of secondary bacteraemia in hospitalised adults with community acquired non-typhoidal Salmonella gastroenteritis. [PDF]

, 2013
BACKGROUND: The clinical significance of bacteraemia secondary to non-typhoidal Salmonella (NTS) gastroenteritis in hospitalised adults is uncertain. METHODS: Adults admitted to a hospital in Liverpool, UK, with NTS gastroenteritis were identified using ...
Beeching, Nicholas J, Cooke, Richard PD, Stephen J Rogerson, Aspinall, EJ, Esther J Aspinall, Harries, Anthony D, Thomas, Sherine, Nicholas J Beeching, Richard PD Cooke, Aspinall, Esther J., Cooke, RPD, Harries, AD, Parry, Christopher M, Aspinall, Esther J, Rogerson, Stephen J, Parry, CM, Rogerson, Stephen J., Anthony D Harries, Harries, Anthony D., Christopher M Parry, Beeching, Nicholas, Thomas, S, Cooke, Richard P.D., Parry, Christopher, Sherine Thomas, Rogerson, SJ, Beeching, NJ   +26 more
core   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

HOSPITAL ACQUIRED INFECTIONS

The Professional Medical Journal, 2010
Nosocomial infections may be defined as the infections which develop within hospital. There are different types of  microorganisms which are involved along with other agents for the spread of these infections. Knowledge about the spread and prevention of these infections is the basic step for control.
SHAZIA QAYYUM, BUSHRA Waqas, ABDUL SATTAR   +2 more
openaire   +3 more sources