Results 41 to 50 of about 273,297 (275)

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Feasibility of forecasting future critical care bed availability using bed management data

BMJ Health & Care Informatics
Objectives This project aims to determine the feasibility of predicting future critical care bed availability using data-driven computational forecast modelling and routinely collected hospital bed management data.Methods In this proof-of-concept, single-
Laura Moss, John Palmer, Aileen Neilson, Areti Manataki, Tsz-Yan Milly Lo   +4 more
doaj   +1 more source

The Optimal Number of Hospital Beds Under Uncertainty: A Costs Management Approach [PDF]

Journal of Optimization in Industrial Engineering, 2018
Equipping hospital beds uses a great deal of a hospital''''s resources. Therefore, it is essential to consider the hospital beds'''' efficiency. To increase its efficiency, a fuzzy unrestricted model for managing hospital expenses is presented in this ...
Saeed Khalili, Mohammad Ghodoosi, Javad Hasanpour   +2 more
doaj   +1 more source

Impact of Hospital Bed Shortages on the Containment of COVID-19 in Wuhan

International Journal of Environmental Research and Public Health, 2020
The global outbreak of COVID-19 has caused worrying concern amongst the public and health authorities. The first and foremost problem that many countries face during the outbreak is a shortage of medical resources. In order to investigate the impact of a
Weike Zhou, Aili Wang, Xia Wang, R. Cheke, Yanni Xiao, Sanyi Tang   +5 more
semanticscholar   +1 more source

Bed Capacity and Utilization at Hospitals With Trauma Centers

JAMA Surgery
Importance As trauma care–related demand continues to rise, the US trauma system’s current utilization and ability to accommodate surges from mass casualty events or disasters remain uncertain. Understanding existing trauma bed occupancy and reserve capacity is essential for national preparedness.
Acharya, Pawan, Staudenmayer, Kristan, Jarman, Molly P., Griffin, Russell, Kerby, Jeffrey D., Hashmi, Zain G.   +5 more
openaire   +3 more sources

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Unit managers between fluctuating demand and fixed staffing: a quantitative study in psychiatric nursing

Frontiers in Health Services
Balancing patient demand with nurse staffing remains a central challenge in inpatient care. In psychiatric settings, patient-side fluctuations create variability that is difficult to reconcile with fixed rosters and limited staffing flexibility.
Michael Ketzer, Michael Ketzer, Beatrice Gehri, Beatrice Gehri, André Nienaber, André Nienaber, Christian G. Huber, Michael Simon   +7 more
doaj   +1 more source

Navigating hospitals safely through the COVID-19 epidemic tide: Predicting case load for adjusting bed capacity

Infection control and hospital epidemiology, 2020
Background: The pressures exerted by the coronavirus disease 2019 (COVID-19) pandemic pose an unprecedented demand on healthcare services. Hospitals become rapidly overwhelmed when patients requiring life-saving support outpace available capacities ...
T. Donker, Fabian Bürkin, M. Wolkewitz, Christian Haverkamp, D. Christoffel, Oliver Kappert, T. Hammer, Hans-Jörg Busch, P. Biever, J. Kalbhenn, H. Bürkle, W. Kern, Frederik Wenz, H. Grundmann   +13 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source