Results 31 to 40 of about 623,813 (255)

Cost Assessment of Inpatient Care Episodes of Stroke in Romania

Frontiers in Public Health, 2020
Introduction: Stroke is the second leading cause of death worldwide and Romania is no exception. There is a high economic burden associated with the treatment of stroke patients, which puts pressure on the healthcare budget.
László Lorenzovici, László Lorenzovici, Andrea Székely, Marcell Csanádi, Péter Gaál   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Pathogen distribution, antimicrobial resistance and attributable cost analysis of neonatal sepsis in neonatal intensive care units: a propensity score matching study

Frontiers in Pediatrics
BackgroundNeonatal sepsis (NS) is a serious infection in neonatal intensive care units (NICUs) that treatment challenges due to evolving antimicrobial resistance and a substantial healthcare burden.
Bingyan Zhang, Peiyun Zhou, Zongke Long, Zhiwei Wang, Zhiwei Wang, Lan Gao, Siya Meng, Fang Xue, Xiaorong Luan, Xiaorong Luan   +9 more
doaj   +1 more source

Association between transfusion status and clinical and economic outcomes in patients with myelodysplastic syndromes from the physicians' perspective

Cancer Reports, 2023
Background The current study investigated physicians' understanding of the impact of transfusion status (TS) on clinical and economic outcomes in patients with myelodysplastic syndromes (MDS).
Shaloo Gupta, Austin G. Kulasekararaj, Halley Costantino, Jay Grisolano, Jackson Tang, Shalon Jones, Derek Tang   +6 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Analysis of hospital and payer costs of care: aggressive warming versus routine warming in abdominal major surgery

Frontiers in Public Health, 2023
BackgroundHypothermia is common and active warming is recommended in major surgery. The potential effect on hospitals and payer costs of aggressive warming to a core temperature target of 37°C is poorly understood.MethodsIn this sub-analysis of the ...
Shujia Song, Lijian Pei, Hongda Chen, Yuelun Zhang, Chen Sun, Jie Yi, Yuguang Huang   +6 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Evaluating the Waste Prevention Potential of a Multi- versus Single-Use Surgical Stapler

Risk Management and Healthcare Policy, 2021
Markus Meissner,1 Sabrina Lichtnegger,1 Scott Gibson,2 Rhodri Saunders2 1Austrian Institute of Ecology, Vienna, Austria; 2Coreva Scientific GmbH & Co KG, Koenigswinter, GermanyCorrespondence: Rhodri SaundersCoreva Scientific GmbH & Co KG, Koenigswinter ...
Meissner M, Lichtnegger S, Gibson S, Saunders R   +3 more
doaj  

The Micro Hand S vs. da Vinci Surgical Robot-Assisted Surgery on Total Mesorectal Excision: Short-Term Outcomes Using Propensity Score Matching Analysis

Frontiers in Surgery, 2021
Objective: To compare the operation mode and clinical short-term outcomes of the Micro Hand S and the da Vinci surgical robot, we chose total mesorectal excision (TME) as the standard procedure for its good reflection of robot-assisted surgery advantages.
Yijia Zeng, Guohui Wang, Zheng Li, Hao Lin, Shaihong Zhu, Bo Yi   +5 more
doaj   +1 more source