Results 41 to 50 of about 623,813 (255)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

An Exploratory Analysis of the Association Between Hospital Labor Costs and the Quality of Care

Risk Management and Healthcare Policy, 2023
Brad Beauvais,1 Clemens Scott Kruse,1 Zo Ramamonjiarivelo,1 Rohit Pradhan,1 Keya Sen,1 Lawrence Fulton2 1School of Health Administration, Texas State University, San Marcos, TX, USA; 2Woods College of Advancing Studies, Boston College, Chestnut Hill, MA,
Beauvais B, Kruse CS, Ramamonjiarivelo Z, Pradhan R, Sen K, Fulton L   +5 more
doaj  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Investigation of the Effect of Aging on Health Costs: A Systematic Review

پژوهش‌های سلامت‌محور, 2020
Investigation of the Effect of Aging on Health Costs: A Systematic Review   Rezapour Aziz1, Arabloo Jalal2, Alipour Vahid3*, Alipour Samira4   1. Associate Professor, Health Management and Economics Research Center, Iran University of Medical Sciences ...
Aziz Rezapour, Jalal Arabloo, Vahid Alipour, Samira Alipour   +3 more
doaj  

Evaluation of hospitalization costs for diabetic pregnant women in a University Hospital in the interior of São Paulo State - 10.4025/actascihealthsci.v34ispec.10460

Acta Scientiarum. Health Sciences, 2012
This study aimed at identifying the hospitalization costs of pregnant women with Diabetes Mellitus (DM) at a University Hospital. It is an observational, quantitative study with descriptive data analysis.
Silvana Andrea Molina Lima, Ana Claudia Molina Cavassini, Ligia Nogueira Manso, Marilza Vieira Cunha Rudge   +3 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Impact of planned delivery mode on neonatal outcomes and costs in twin pregnancies in KenyaAJOG Global Reports at a Glance

AJOG Global Reports
Background: Twin pregnancies are associated with higher risks of adverse neonatal outcomes compared to singleton pregnancies. The choice of delivery mode, when twin A presents cephalic, remains a subject of debate.
Fred O. Omondi, MBChB, Meghan K. Murphy, DO, Moselle M. Stark, MD, Cheryl B. Cowles, MD, Phillip C. Greig, MD, Benoît J. Ndikumana, MMed (Obs & Gyn), Robert K. Parker, MD, MPH   +6 more
doaj   +1 more source