Results 51 to 60 of about 1,609,172 (298)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Evaluating the Waste Prevention Potential of a Multi- versus Single-Use Surgical Stapler
Markus Meissner,1 Sabrina Lichtnegger,1 Scott Gibson,2 Rhodri Saunders2 1Austrian Institute of Ecology, Vienna, Austria; 2Coreva Scientific GmbH & Co KG, Koenigswinter, GermanyCorrespondence: Rhodri SaundersCoreva Scientific GmbH & Co KG, Koenigswinter ...
Meissner M +3 more
doaj
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
An Exploratory Analysis of the Association Between Hospital Labor Costs and the Quality of Care
Brad Beauvais,1 Clemens Scott Kruse,1 Zo Ramamonjiarivelo,1 Rohit Pradhan,1 Keya Sen,1 Lawrence Fulton2 1School of Health Administration, Texas State University, San Marcos, TX, USA; 2Woods College of Advancing Studies, Boston College, Chestnut Hill, MA,
Beauvais B +5 more
doaj
Aiming Higher: Results From a State Scorecard on Health System Performance [PDF]
Assesses state variation across key dimensions of health system performance -- access, quality, avoidable hospital use and costs, equity, and healthy lives -- and assigns overall state rankings as well as ranks on each ...
Cathy Schoen +4 more
core
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Investigation of the Effect of Aging on Health Costs: A Systematic Review
Investigation of the Effect of Aging on Health Costs: A Systematic Review Rezapour Aziz1, Arabloo Jalal2, Alipour Vahid3*, Alipour Samira4 1. Associate Professor, Health Management and Economics Research Center, Iran University of Medical Sciences ...
Aziz Rezapour +3 more
doaj
Hospital and Physician Capacity Update [PDF]
Offers an alternative view of healthcare costs by examining trends in hospital capacity and healthcare labor across regions. Outlines how effective management of healthcare capacity would enable affordable quality care that meets patient needs and ...
David C. Goodman +2 more
core

