Results 171 to 180 of about 460,810 (250)

R pyocin sensitivity of <i>Pseudomonas aeruginosa</i> clinical isolates from different disease types. [PDF]

J Med Microbiol
Deng Y, Wang M, Chopra C, Shelburne SA, Miller WR, Kirienko NV.   +5 more
europepmc   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

The Effect of Procoagulants on Radial Artery Cardiac Catheterization Outcomes: A Systematic Review and Network Meta-Analysis

Journal of Interventional Cardiology
Ritin Fernandez, Amir Masoud Sharifnia, Philip Newton, Leila Mohammadi, Kerry J. Inder, Tom Ford, Astin Lee   +6 more
doaj   +1 more source

Sequential in vivo CRISPR screens identify the clonal dominance of <i>Nf1</i> loss in long-term hematopoiesis. [PDF]

Blood Sci
Yuan S, Wu Q, Yin T, Chen L, Zhang B, Li P, Xie X, Sun G, Cheng T, Wei J, Cheng H.   +10 more
europepmc   +1 more source

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

Advanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng, Xinlei Huang, Xiang Zhou, Dian Meng, Ziyue Qiao, Zhiyuan Yuan, Lixin Cheng   +6 more
wiley   +1 more source

Erratum to: “Peer-reviewed publications in orthopaedic surgery from lower income countries: A comparative analysis”

SICOT-J
Sabharwal Sanjeev, Leung Andrea, Bwemelo Joel Johansen, Rodarte Patricia, Taylor Annelise S., Singh Gurbinder, Tan Josephine, Trott Richard   +7 more
doaj   +1 more source

The applicability of the new media platform "Urological Surgery Learning Notes" in continuing medical education for urologists. [PDF]

BMC Med Educ
Tang S, Hong P, Zhu G, Guo W, Zhao X, Chen J, Liu L, Zhang H, Xiao C, Liu K, Lu J, Ma L, Hong K, Zhang S, Liu Z.   +14 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Perspectives on the injured child's hospital discharge process and opportunities for improvement: a scoping review protocol. [PDF]

BMJ Open
Akers E, Ameratunga S, Wilkinson-Meyers L, Adams M, Te Ao B.   +4 more
europepmc   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source