Results 111 to 120 of about 1,760,346 (311)

HYPONATREMIA AS A PROGNOSTIC INDICATOR IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN ADMITTED IN PAEDIATRIC INTENSIVE CARE UNIT

Pakistan Armed Forces Medical Journal, 2021
Objective: To study the serum sodium levels in patients of lower respiratory tract infections admitted in the paediatric intensive care unit with their prognosis. Study Design: Prospective observational study.
Naila Hamid, Muhammad Faisal Shafique, Qamar-uz-Zaman ., Hafza Niaz   +3 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Association Between Red Blood Cell Distribution Width–Albumin Ratio and Hospital Mortality in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit: A Retrospective Study

International Journal of COPD, 2022
Yuanjie Qiu, Yan Wang, Nirui Shen, Qingting Wang, Limin Chai, Jin Liu, Yuqian Chen, Manxiang Li Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of ...
Qiu Y, Wang Y, Shen N, Wang Q, Chai L, Liu J, Chen Y, Li M   +7 more
doaj  

Hospital Standardized Mortality Ratio: Consequences of Adjusting Hospital Mortality with Indirect Standardization

PLoS ONE, 2013
The hospital standardized mortality ratio (HSMR) is developed to evaluate and improve hospital quality. Different methods can be used to standardize the hospital mortality ratio. Our aim was to assess the validity and applicability of directly and indirectly standardized hospital mortality ratios.Retrospective scenario analysis using routinely ...
Pouw, ME, Peelen, LM, Lingsma, Hester, Pieter, D, Steyerberg, Ewout, Kalkman, CJ, Moons, KGM   +6 more
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Factors of Hospital Mortality in Men and Women with ST-Elevation Myocardial Infarction – An Observational, Retrospective, Single Centre Study [PDF]

, 2023
Martin Marinsek,1,* David Šuran,2,* Andreja Sinkovic1,3,* 1Department of Medical Intensive Care, University Clinical Centre Maribor, Maribor, 2000, Slovenia; 2Department of Cardiology, University Clinical Centre Maribor, Maribor, 2000 ...
Marinsek M, Šuran D, Sinkovic A
core  

Factors Affecting Duration of Hospital Stay in Deceased COVID-19 Patients

International Journal of General Medicine, 2023
Ercan Kurtipek,1 Mehmet Mermer,1 Bilgenur Yıldırım,1 Mehmet Akif Yazar,2 Mustafa Duran,3 Faysal Duksal4 1Department of Chest Diseases, University of Health Sciences, Konya City Hospital, Karatay, Konya, Turkey; 2Department of ...
Kurtipek E, Mermer M, Yıldırım B, Yazar MA, Duran M, Duksal F   +5 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Do acute elevations of serum creatinine in primary care engender an increased mortality risk? [PDF]

, 2014
Background: The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment.
Paul Bassett, Paul E Stevens, Bassett, Paul, Wheeler, Toby, Stevens, Paul E., Christopher KT Farmer, Helen Hobbs, Hobbs, Helen, Jean Irving, Irving, Jean, Michael Bedford, Bedford, Michael, Farmer, Christopher K., Toby Wheeler   +13 more
core   +1 more source