Results 101 to 110 of about 1,758,521 (311)

National Audit of Hospital Mortality Annual Report 2018

, 2021
This is the fourth National Audit of Hospital Mortality Annual Report. It provides mortality information across six key diagnoses: acute myocardial infarction (heart attack), heart failure, ischaemic stroke, haemorrhagic stroke, chronic obstructive ...
The National Office of Clinical Audit (NOCA) (11202798), Simon Jones (26390), Deirdre Burke (10880003), Aisling Connolly (11648018), Bridget Egan (7949264), Fionnola Kelly (11648019), Declan McKeown (11662004), Alan Egan (8010032), The National Audit of Hospital Mortality Governance Committee (11662130)   +8 more
core   +1 more source

Epidemiology of Under-5 Mortality Rate in Ardabil Province, Iran 2011-2015

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: The Child Mortality Index is an important part of the Millennium Development Goals. Every year, 6 million children die in the world.
Amin Ataey, Abbas Alipour, Soheila Khodakarim, Ardeshir Khosravi   +3 more
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Survival prediction for heart failure complicated by sepsis: based on machine learning methods

Frontiers in Medicine
BackgroundHeart failure is a cardiovascular disorder, while sepsis is a common non-cardiac cause of mortality. Patients with combined heart failure and sepsis have a significantly higher mortality rate and poor prognosis, making early identification of ...
Qitian Zhang, Lizhen Xu, Weibin He, Xinqi Lai, Xiaohong Huang   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Dynamics of hospital mortality in COVID-19 pandemia [PDF]

Терапевтический архив
Background. During the pandemic of coronavirus infection (COVID-19) caused by a virus SARS-CoV-2 there has been significant variability in symptoms of the disease over time, severity of the course and in particular hospital mortality.
Diana F. Gareeva, Irina A. Lakman, Alexander A. Agapitov, Liana F. Sadikova, Paruir A. Davtian, Valeriia L. Kayumova, Guzel M. Nurtdinova, Elena A. Badykova, Magomed S. Kurbanov, Islam R. Idigov, Lukas Fiedler, Lukas-Jaroslaw Motloch, Аnna-Maria Dieplinger, Venera M. Timiryanova, Naufal Sh. Zagudullin   +14 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

HYPONATREMIA AS A PROGNOSTIC INDICATOR IN LOWER RESPIRATORY TRACT INFECTIONS IN CHILDREN ADMITTED IN PAEDIATRIC INTENSIVE CARE UNIT

Pakistan Armed Forces Medical Journal, 2021
Objective: To study the serum sodium levels in patients of lower respiratory tract infections admitted in the paediatric intensive care unit with their prognosis. Study Design: Prospective observational study.
Naila Hamid, Muhammad Faisal Shafique, Qamar-uz-Zaman ., Hafza Niaz   +3 more
doaj  

Hospital Standardized Mortality Ratio: Consequences of Adjusting Hospital Mortality with Indirect Standardization

PLoS ONE, 2013
The hospital standardized mortality ratio (HSMR) is developed to evaluate and improve hospital quality. Different methods can be used to standardize the hospital mortality ratio. Our aim was to assess the validity and applicability of directly and indirectly standardized hospital mortality ratios.Retrospective scenario analysis using routinely ...
Pouw, ME, Peelen, LM, Lingsma, Hester, Pieter, D, Steyerberg, Ewout, Kalkman, CJ, Moons, KGM   +6 more
openaire   +4 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source