Results 81 to 90 of about 7,369,841 (409)

What is the real impact of acute kidney injury? [PDF]

, 2014
Background: Acute kidney injury (AKI) is a common clinical problem. Studies have documented the incidence of AKI in a variety of populations but to date we do not believe the real incidence of AKI has been accurately documented in a district general ...
A Arije, A Lewington, Census population, Christopher KT Farmer, DJ Askenazi, EA Hoste, ED Siew, ED Siew, ED Siew, GM Chertow, H Quan, Health and Social Care Information Centre, HS Kohli, J Hegarty, J Stewart, JE Hux, JL Xue, JP Lafrance, KS Chugh, Michael Bedford, MM Levy, NV Kolhe, O Liangos, P Vachvanichsanong, Paul E Stevens, PE Stevens, PG Metnitz, R Bellomo, RL Mehta, RL Mehta, S Uchino, SS Waikar, T Ali, Toby WK Wheeler, W Metcalfe   +34 more
core   +2 more sources

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score

British medical journal, 2020
Objective To develop and validate a pragmatic risk score to predict mortality in patients admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective observational cohort study.
S. Knight, A. Ho, R. Pius, I. Buchan, G. Carson, T. Drake, J. Dunning, C. Fairfield, C. Gamble, C. A. Green, Rishi K. Gupta, S. Halpin, H. Hardwick, K. Holden, P. Horby, C. Jackson, K. Mclean, L. Merson, J. Nguyen-Van-Tam, L. Norman, M. Noursadeghi, P. Olliaro, M. Pritchard, C. Russell, Catherine A. Shaw, Aziz Sheikh, Tommy Solomon, C. Sudlow, O. Swann, L. Turtle, P. Openshaw, J. Baillie, M. Semple, A. Docherty, E. Harrison, J. Baillie, M. Semple, P. Openshaw, G. Carson, B. Alex, Benjamin Bach, W. Barclay, D. Bogaert, M. Chand, Graham S. Cooke, A. Docherty, J. Dunning, A. da Silva Filipe, T. Fletcher, C. A. Green, E. Harrison, J. Hiscox, A. Ho, P. Horby, S. Ijaz, S. Khoo, P. Klenerman, Andrew Law, W. Lim, A. Mentzer, L. Merson, A. Meynert, M. Noursadeghi, S. Moore, M. Palmarini, W. Paxton, G. Pollakis, NicholasS . C. Price, A. Rambaut, David L. Robertson, C. Russell, V. Sancho-Shimizu, J. Scott, L. Sigfrid, Tommy Solomon, S. Sriskandan, D. Stuart, C. Summers, R. Tedder, E. Thomson, R. Thwaites, L. Turtle, M. Zambon, H. Hardwick, C. Donohue, Jane Ewins, W. Oosthuyzen, Fiona Griffiths, L. Norman, R. Pius, Tom M. Drake, C. Fairfield, S. Knight, K. Mclean, D. Murphy, Catherine A. Shaw, Joanne Dalton, M. Girvan, Eglė Savičiūtė, S. Roberts, Janet R Harrison, Laura Marsh, M. Connor, S. Halpin, C. Jackson, C. Gamble, G. Leeming, Ross Hendry, James Scott-Brown, W. Greenhalf, V. Shaw, Sarah E. McDonald, K. Ahmed, J. Armstrong, M. Ashworth, I. G. Asiimwe, S. Bakshi, S. Barlow, Laura J. Booth, B. Brennan, K. Bullock, Benjamin W. A. Catterall, Jordan J. Clark, Emily Clarke, Sarah J. Cole, L. Cooper, H. Cox, Christopher Davis, Oslem Dincarslan, Chris Dunn, P. Dyer, A. Elliott, A. Evans, Lewis W. S. Fisher, T. Foster, Isabel García-Dorival, W. Greenhalf, P. Gunning, Catherine Hartley, A. Ho, R. L. Jensen, Christopher Jones, T. R. Jones, Shadia Khandaker, K. King, Robyn T Kiy, Chrysa Koukorava, Annette Lake, S. Lant, D. Latawiec, L. Lavelle-Langham, Daniella A. Lefteri, Lauren Lett, Lucia A. Livoti, Maria Mancini, L. McEvoy, J. Mclauchlan, S. Metelmann, N. Miah, J. Middleton, Joyce Mitchell, E. Murphy, R. Penrice-Randal, J. Pilgrim, T. Prince, W. Reynolds, P. Ridley, Debby Sales, V. Shaw, R. Shears, B. Small, Krishanthi S Subramaniam, Agnieska Szemiel, Aislynn Taggart, J. Tanianis-Hughes, Jordan Thomas, E. Trochu, Libby van Tonder, E. Wilcock, J. E. Zhang, K. Adeniji, D. Agranoff, K. Agwuh, D. Ail, A. Alegria, Brian Angus, A. Ashish, Doug Atkinson, S. Bari, G. Barlow, S. Barnass, Nicholas A. Barrett, C. Bassford, D. Baxter, M. Beadsworth, J. Bernatoniene, J. Berridge, N. Best, P. Bothma, D. Brealey, R. Brittain-Long, N. Bulteel, Thomas G Burden, A. Burtenshaw, Vikki Caruth, D. Chadwick, D. Chambler, Nigel Chee, J. Child, S. Chukkambotla, Tom Clark, P. Collini, Catherine Cosgrove, J. Cupitt, Maria-Teresa Cutino-Moguel, P. Dark, Chris Dawson, S. Dervisevic, P. Donnison, S. Douthwaite, I. DuRand, A. Dushianthan, Tristan Dyer, C. Evans, C. Eziefula, Chrisopher Fegan, A. Finn, D. Fullerton, S. Garg, A. Garg, J. Godden, A. Goldsmith, Clive Graham, E. Hardy, S. Hartshorn, D. Harvey, P. Havalda, D. Hawcutt, M. Hobrok, L. Hodgson, Anita Holme, A. Hormis, M. Jacobs, Susan Jain, P. Jennings, A. Kaliappan, V. Kasipandian, S. Kegg, Michael R. Kelsey, J. Kendall, C. Kerrison, I. Kerslake, O. Koch, G. Koduri, G. Koshy, S. Laha, Susan G. Larkin, T. Leiner, P. Lillie, James Limb, V. Linnett, J. Little, M. MacMahon, E. Macnaughton, Ravish Mankregod, Huw Masson, E. Matovu, K. McCullough, R. Mcewen, M. Meda, G. Mills, J. Minton, M. Mirfenderesky, K. Mohandas, Quen Mok, J. Moon, Elinoor Moore, P. Morgan, C. Morris, Katherine Mortimore, S. Moses, Mbiye A Mpenge, R. Mulla, Michael J. Murphy, Megan L. Nagel, T. Nagarajan, M. Nelson, I. Otahal, M. Pais, S. Panchatsharam, Hassan Paraiso, B. Patel, J. Pepperell, M. Peters, M. Phull, S. Pintus, J. Pooni, F. Post, D. Price, R. Prout, N. Rae, H. Reschreiter, Tim Reynolds, Neil Richardson, M. Roberts, D. Roberts, A. Rose, G. Rousseau, Brendan J. Ryan, Taranprit Saluja, A. Shah, Prad Shanmuga, Anil Sharma, A. Shawcross, J. Sizer, Richard Smith, C. Snelson, N. Spittle, N. Staines, T. Stambach, R. Stewart, P. Subudhi, T. Szakmany, K. Tatham, Jordan Thomas, C. Thompson, Robert Thompson, A. Tridente, Darell Tupper-Carey, M. Twagira, A. Ustianowski, N. Vallotton, L. Vincent-Smith, S. Visuvanathan, A. Vuylsteke, S. Waddy, R. Wake, A. Walden, I. Welters, T. Whitehouse, P. Whittaker, A. Whittington, M. Wijesinghe, Martin Williams, Lawrence Wilson, Sarah Wilson, S. Winchester, M. Wiselka, A. Wolverson, D. Wooton, A. Workman, B. Yates, Peter Young   +352 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A Novel Composite Indicator of Predicting Mortality Risk for Heart Failure Patients With Diabetes Admitted to Intensive Care Unit Based on Machine Learning

Frontiers in Endocrinology, 2022
BackgroundPatients with heart failure (HF) with diabetes may face a poorer prognosis and higher mortality than patients with either disease alone, especially for those in intensive care unit.
Boshen Yang, Yuankang Zhu, Xia Lu, Chengxing Shen   +3 more
doaj   +1 more source

Measuring Hospital Mortality

Acute Medicine Journal, 2013
The hospital standardised mortality ratio (HSMR) and the summary hospital mortality index (SHMI) are both in current use in the UK as measures of the performance of acute hospitals. Characteristics of both the acute hospital itself and of its local healthcare environment influence these indices.
openaire   +4 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The Prognostic Role of Mean Platelet Volume (MPV) in Sever Sepsis: is it True? [PDF]

Journal of Kerman University of Medical Sciences, 2019
Background: The purpose of the present study was to examine the role of mean platelet volume (MPV) in comparison with Sequential Organ Failure Assessment (SOFA), quick SOFA (qSOFA), and Mortality in Severe Sepsis in the Emergency Department (MISSED ...
Amirhossein Chalabi, mehdi torabi, Moghaddameh Mirzaee   +2 more
doaj   +1 more source

Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths [PDF]

, 2011
Background: Acceleration of chronic diseases, particularly cardiovascular disease, may increase long-term mortality after community-acquired pneumonia (CAP), but underlying mechanisms are unknown. Persistence of the prothrombotic state that occurs during
A. Murat Kaynar, AM Toschke, CN Serhan, CR Meier, DC Cowper, Derek C. Angus, EA Halm, EB Milbrandt, F Balkwill, FL Brancati, Florian Mayr, GD Lowe, Gina D'Angelo, GT Kinasewitz, GW Waterer, H Putter, I Koivula, J Bordon, J Kasal, J Kelly, JA Kellum, JL Hsu, JL Vincent, John A. Kellum, JU Hedlund, Kaikobad Irani, L Smeeth, Lisa Weissfeld, ME Charlson, MJ Fine, MJ Pencina, MM Doody, MM Levy, MM Samama, NM Sathiakumar, Patricia T. Bozza, PM Ridker, PR Woodhouse, S Yende, S Yende, Sachin Yende, SE Epstein, Tammy Young, TC Clayton, TT Keller, TT Keller, V Kaplan, VF Corrales-Medina, WA Knaus, WB Kannel   +49 more
core   +5 more sources

Neonatal mortality at Leratong Hospital

South African Journal of Child Health, 2018
Background. There has been a high demand for delivery services at Leratong Hospital; however, no study on the causes of neonatal mortality has been conducted. It was therefore essential to identify the causes of newborn deaths so as to implement policies that would advance neonatal care.Objectives.
Moundzika-Kibamba, J C, Nakwa, F L
openaire   +5 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source