Results 111 to 120 of about 926,652 (307)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Knowledge Assessment of Hospital Staff Regarding Biomedical Waste Management in A Tertiary Care Hospital

open access: yesNational Journal of Community Medicine, 2012
Background: Biomedical waste (BMW) is waste generated during diagnosis, treatment or immunization of human beings or animals. Approximately 10-25% of the Bio-Medical waste is hazardous and can be injurious to humans or animals and deleterious to ...
Vishal Bathma   +5 more
doaj  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

The Status of Observing the Charter of Patients’ Rights and Related Factors from the Point of View of Hospitalized Patients

open access: yesJournal of Holistic Nursing and Midwifery, 2020
Introduction: Adherence to patients’ rights is one of the most important ethical issues in the hospital that should be considered. An efficient health system requires active participation and proper interaction between health care recipients and ...
Seyedeh Narjes Fazeli   +3 more
doaj  

Paediatric staff photo

open access: yes
Black and white photo of several staff members in what appears to be the Paediatric ...
Modbury Hospital
core  

Shangri La, Los Angeles County Hospital

open access: yes, 1928
Shangri La is what the intern and resident quarters at the Los Angeles County Hospital was named.
Los Angeles County Hospital staff photograph
core  

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

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