Results 131 to 140 of about 926,652 (307)
نشریه پرستاری ایران, 2012 Background & Aims: Spirituality and its components due to their effect on psychological constructs and their potential influence on organizational performance have been the researchers’ concerns in recent years.
N Ghahremani, MA Nadi
doaj
Minute book, Board of Governors, Holy Cross Hospital
, 1902 Scan of a book of minutes from staff meetings at Holy Cross Hospital in Salt Lake City, Utah, from 1902 through 1918, and related ...
Holy Cross Hospital (Salt Lake City, Utah)
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Advanced Science, EarlyView.This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang +10 more
wiley +1 more source
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Massachusetts Osteopathic Hospital Memorandum
, 1954 Memorandum to all hospital staff announcing new staff and staff departures, addressing issues at the hospital, the board of trustees, and fundraising.https://dune.une.edu/kimballcollection/1007/thumbnail ...
Massachusetts Osteopathic Hospital
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Advanced Science, EarlyView.ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang +7 more
wiley +1 more source
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This study was a qualitative examination of patient and staff experiences within a redeveloping acute NHS hospital Trust in England.
Pajak, Sarah
core
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source