Results 101 to 110 of about 270,120 (271)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Cost-containment in health care: The case of Spain from the eighties up to 1997 [PDF]
The purpose of this paper is to provide an overview of the evolution of health care expenditure in Spain during the period 1980-1997, and henceforth to comment on the cost containment measures put forward to control its growth.
Guillem López
core
Nothing but the Truth, take two: fighting for the reader in the Tlatelolco 1968 discourse [PDF]
, 2012 The hypothesis put forward in this project is that there are two mechanisms of creating a collective memory of the event: one is hegemonic (dominated by state discourses and, potentially, academic studies of the shooting), and the other is posthegemonic (
Carpenter, Victoria
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Modelo de organizacion de una unidad de emergencia hospitalaria en funcion de la demanda observada [PDF]
, 1997 145 p.Se propone una metodología general que permite, adecuando la oferta de horas profesionales existente en las Unidades de Emergencia de los hospitales públicos a la demanda observada, una organización más eficiente de ellas.
Baechler Rojas, Roberto (Prof. Guía) +2 more
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Evaluación de la calidad en la atención en elárea de farmacia de los hospitales: antonio Lenin Fonseca, Bertha Calderón Roque y psicosocial José Dolores Fletes, Septiembre-Noviembre 2016 [PDF]
, 2017 La calidad es un concepto clave hoy en día para los servicios sanitarios y la Organización Mundial de la Salud (OMS) la define como: un alto nivel de excelencia profesional, un uso eficiente de los recursos, un mínimo de riesgos para el paciente y un ...
Caballero Barrera, Maykelin Josmara +2 more
core
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source